Hanshen Yang

Targeting ubiquitin-specific protease 8 sensitizes anti-programmed death-ligand 1 immunotherapy of pancreatic cancer

Hanshen Yang, Xiaozhen Zhang, Mengyi Lao et al. · Cell Death and Differentiation · 2022 · 76 citations · Full text

Combination cancer immunotherapy targeting TNFR2 and PD-1/PD-L1 signaling reduces immunosuppressive effects in the microenvironment of pancreatic tumors

Xiaozhen Zhang, Mengyi Lao, Jian Xu et al. · Journal for ImmunoTherapy of Cancer · 2022 · 70 citations · Full text

Elevated protein lactylation promotes immunosuppressive microenvironment and therapeutic resistance in pancreatic ductal adenocarcinoma

Kang Sun, Xiaozhen Zhang, Jiatao Shi et al. · Journal of Clinical Investigation · 2025 · 56 citations · Full text

Targeting cancer-associated fibroblast autophagy renders pancreatic cancer eradicable with immunochemotherapy by inhibiting adaptive immune resistance

Xiaozhen Zhang, Mengyi Lao, Hanshen Yang et al. · Autophagy · 2024 · 53 citations · Full text

Targeting MFAP5 in cancer-associated fibroblasts sensitizes pancreatic cancer to PD-L1-based immunochemotherapy via remodeling the matrix

Yi Duan, Xiaozhen Zhang, Honggang Ying et al. · Oncogene · 2023 · 45 citations · Full text