Uma Lakshmanan

CRISPR-based gene editing enables <i>FOXP3</i> gene repair in IPEX patient cells

Marianne Goodwin, Uma Lakshmanan, Suzette Shipp et al. · Science Advances · 2020 · 113 citations · Full text

Life Sciences, Genetics, Molecular Biology +15

Epigenetic and immunological indicators of IPEX disease in subjects with FOXP3 gene mutation

Mansi Narula, Uma Lakshmanan, Šimon Borna et al. · Journal of Allergy and Clinical Immunology · 2022 · 34 citations · Full text

Life Sciences, Genetics, Immunology +16

Identification of unstable regulatory and autoreactive effector T cells that are expanded in patients with <i>FOXP3</i> mutations

Šimon Borna, Esmond Lee, Jason Nideffer et al. · Science Translational Medicine · 2023 · 24 citations · Full text

Life Sciences, Genetics, Immunology +17