Jumpei Morimoto

Discovery of Macrocyclic Peptides Armed with a Mechanism‐Based Warhead: Isoform‐Selective Inhibition of Human Deacetylase SIRT2

Jumpei Morimoto, Yuuki Hayashi, Hiroaki Suga · Angewandte Chemie International Edition · 2012 · 154 citations

Peptide Engineering, Molecular Biology, Peptide Science +17

<i>In Vitro</i> Selection of Anti-Akt2 Thioether-Macrocyclic Peptides Leading to Isoform-Selective Inhibitors

Yuuki Hayashi, Jumpei Morimoto, Hiroaki Suga · ACS Chemical Biology · 2012 · 131 citations

Ribosomal Synthesis of Bicyclic Peptides via Two Orthogonal Inter-Side-Chain Reactions

Yusuke Sako, Jumpei Morimoto, Hiroshi Murakami et al. · Journal of the American Chemical Society · 2008 · 119 citations

Medicinal Chemistry, Various Peptides, Bicyclic Peptides +15

Flexizymes: Their Evolutionary History and the Origin of Catalytic Function

Jumpei Morimoto, Yuuki Hayashi, Kazuhiro Iwasaki et al. · Accounts of Chemical Research · 2011 · 103 citations

Cyanomethyl Ester, Engineering, Molecular Biology +20

Structural Basis for Potent Inhibition of SIRT2 Deacetylase by a Macrocyclic Peptide Inducing Dynamic Structural Change

Kenichiro Yamagata, Yuki Goto, Hiroshi Nishimasu et al. · Structure · 2014 · 94 citations · Full text

Signal Transduction, Biochemistry, Natural Sciences +10