I. McConnell

Transmissions to mice indicate that ‘new variant’ CJD is caused by the BSE agent

M. E. Bruce, Robert Will, James W. Ironside et al. · Nature · 1997 · 2K citations

Autoimmune Disease, Disease Mechanism, Immunology +8

129/Ola mice carrying a null mutation in PrP that abolishes mRNA production are developmentally normal

Jean Manson, Alan R. Clarke, M.L. Hooper et al. · Molecular Neurobiology · 1994 · 567 citations

Knockout Mouse, Developmental Biology, Developmental Genetics +9

The disease characteristics of different strains of scrapie in Sinc congenic mouse lines: implications for the nature of the agent and host control of pathogenesis

M. E. Bruce, I. McConnell, H. Fraser et al. · Journal of General Virology · 1991 · 384 citations

Scrapie Strain, Genetics, Pathology +19

PrP gene dosage determines the timing but not the final intensity or distribution of lesions in scrapie pathology.

Jean Manson, Alan R. Clarke, Patricia McBride et al. · PubMed · 1994 · 269 citations

Strain characterization of natural sheep scrapie and comparison with BSE

Moira E. Bruce, Aileen Boyle, Simon Cousens et al. · Journal of General Virology · 2002 · 209 citations

Rodent-borne Diseases, Animal Science, Pathogenesis +15