I. McConnell

Transmissions to mice indicate that ‘new variant’ CJD is caused by the BSE agent

M. E. Bruce, Robert Will, James W. Ironside et al. · Nature · 1997 · 2K citations

Life Sciences, Genetics, Molecular Genetics +3

129/Ola mice carrying a null mutation in PrP that abolishes mRNA production are developmentally normal

Jean Manson, Alan R. Clarke, M.L. Hooper et al. · Molecular Neurobiology · 1994 · 570 citations

Life Sciences, Genetics, Molecular Biology +11

The disease characteristics of different strains of scrapie in Sinc congenic mouse lines: implications for the nature of the agent and host control of pathogenesis

M. E. Bruce, I. McConnell, H. Fraser et al. · Journal of General Virology · 1991 · 384 citations

Veterinary Medicine, Genetics, Infectious Diseases +15

PrP gene dosage determines the timing but not the final intensity or distribution of lesions in scrapie pathology.

Jean Manson, Alan R. Clarke, Patricia McBride et al. · PubMed · 1994 · 269 citations

Veterinary Medicine, Molecular Biology, Molecular Genetics +13

A single amino acid alteration (101L) introduced into murine PrP dramatically alters incubation time of transmissible spongiform encephalopathy

Jean Manson, Elizabeth R. Jamieson, Herbert Baybutt et al. · The EMBO Journal · 1999 · 243 citations · Full text

Veterinary Medicine, Molecular Biology, Neurobiology +11