Luigi Alfano

Molecular Mechanism of 17-Allylamino-17-demethoxygeldanamycin (17-AAG)-induced AXL Receptor Tyrosine Kinase Degradation

Gnana P. Krishnamoorthy, Teresa Guida, Luigi Alfano et al. · Journal of Biological Chemistry · 2013 · 53 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Signal Transduction +9

Depletion of the RNA binding protein HNRNPD impairs homologous recombination by inhibiting DNA-end resection and inducing R-loop accumulation

Luigi Alfano, Antonella Caporaso, Angela Altieri et al. · Nucleic Acids Research · 2019 · 52 citations · Full text

Dna-end Resection, Vitro Dna Resection, Genetics +18

NONO regulates the intra-S-phase checkpoint in response to UV radiation

Luigi Alfano, Caterina Costa, Anthony Caporaso et al. · Oncogene · 2015 · 36 citations

Signal Transduction, Uv Radiation, Cell Division +6

RBL2/p130 is a direct AKT target and is required to induce apoptosis upon AKT inhibition in lung cancer and mesothelioma cell lines

Francesca Pentimalli, Iris Maria Forte, Luca Esposito et al. · Oncogene · 2018 · 31 citations

Oncology, Direct Akt Target, Medicine +9

Abrogating G₂/M checkpoint through WEE1 inhibition in combination with chemotherapy as a promising therapeutic approach for mesothelioma

Paola Indovina, Eleonora Marcelli, Domenico Di Marzo et al. · Cancer Biology & Therapy · 2014 · 25 citations · Full text

Promising Therapeutic Approach, Tumor Biology, Malignant Disease +14