Mutations in <i>TAC1B</i> : a Novel Genetic Determinant of Clinical Fluconazole Resistance in Candida auris

Jeffrey M. Rybak, José F. Muñoz, Katherine S. Barker, +10

mBio

Characterization of the sterol 14α‐demethylases of <i>Fusarium graminearum</i> identifies a novel genus‐specific <scp>CYP</scp>51 function

Jieru Fan, Martin Urban, Josie E. Parker, +6

New Phytologist

Identification and Characterization of Four Azole-Resistant <i>erg3</i> Mutants of <i>Candida albicans</i>

Claire M. Martel, Josie E. Parker, Oliver Bader, +5

Antimicrobial Agents and Chemotherapy

Total Sterol FractionFungal Cell BiologyGeneticsClinical MycologyAntimicrobial Chemotherapy +17

The Clinical Candidate VT-1161 Is a Highly Potent Inhibitor of Candida albicans CYP51 but Fails To Bind the Human Enzyme

Andrew G. S. Warrilow, Claire M. Hull, Josie E. Parker, +6

Antimicrobial Agents and Chemotherapy

A Clinical Isolate of <i>Candida albicans</i> with Mutations in <i>ERG11</i> (Encoding Sterol 14α-Demethylase) and <i>ERG5</i> (Encoding C22 Desaturase) Is Cross Resistant to Azoles and Amphotericin B

Claire M. Martel, Josie E. Parker, Oliver Bader, +4

Antimicrobial Agents and Chemotherapy

Clinical IsolateTotal Sterol FractionFungal Cell BiologyPathologyClinical Mycology +16

Azole Affinity of Sterol 14α-Demethylase (CYP51) Enzymes from Candida albicans and Homo sapiens

Andrew G. S. Warrilow, Josie E. Parker, Diane Kelly, +1

Antimicrobial Agents and Chemotherapy

Drug TargetFungal Cell BiologyMolecular BiologyEscherichia ColiAntimicrobial Chemotherapy +20

The negative cofactor 2 complex is a key regulator of drug resistance in Aspergillus fumigatus

Takanori Furukawa, Norman van Rhijn, Marcin G. Fraczek, +20

Nature Communications

Impact of Recently Emerged Sterol 14α-Demethylase (CYP51) Variants of Mycosphaerella graminicola on Azole Fungicide Sensitivity

H. J. Cools, Jonathan G.L. Mullins, B. A. Fraaije, +4

Applied and Environmental Microbiology

Molecular Mechanisms of Drug Resistance in Clinical Candida Species Isolated from Tunisian Hospitals

Jamel Eddouzi, Josie E. Parker, Luís A. Vale-Silva, +5

Antimicrobial Agents and Chemotherapy

Microbial PathogensFungal Cell BiologyClinical MycologyAntimicrobial ChemotherapySterol Analysis +19

In vivo emergence of high-level resistance during treatment reveals the first identified mechanism of amphotericin B resistance in Candida auris

Jeffrey M. Rybak, Katherine S. Barker, José F. Muñoz, +8

Clinical Microbiology and Infection

Antifungal AgentAntifungal AgentsMedicineAmphotericin B ResistanceClinical Mycology +7