Botulinum A Toxin Therapy: Neutralizing and Nonneutralizing Antibodies—Therapeutic Consequences

Hilke Göschel, Kai Wohlfarth, Jürgen Frevert, +2

Experimental Neurology

ToxinologyImmunologyTherapeutic VaccineA Toxin TherapyImmunotherapeutics +2

The synaptic vesicle protein 2C mediates the uptake of botulinum neurotoxin A into phrenic nerves

Stefan Mahrhold, Andreas Rummel, Hans Bigalke, +2

FEBS Letters

Synaptotagmins I and II Act as Nerve Cell Receptors for Botulinum Neurotoxin G

Andreas Rummel, Tino Karnath, Tina Henke, +2

Journal of Biological Chemistry

The H_CC‐domain of botulinum neurotoxins A and B exhibits a singular ganglioside binding site displaying serotype specific carbohydrate interaction

Andreas Rummel, Stefan Mahrhold, Hans Bigalke, +1

Molecular Microbiology

Full-length NeurotoxinsBiochemistryNatural SciencesBotulinum NeurotoxinsGlycobiology +12

Identification of the protein receptor binding site of botulinum neurotoxins B and G proves the double-receptor concept

Andreas Rummel, Timo Eichner, Tanja Weil, +8

Proceedings of the National Academy of Sciences

NeurotransmitterImmunologyMolecular BiologyCytoskeletonCause Muscle Paralysis +17

Botulinum neurotoxins C, E and F bind gangliosides via a conserved binding site prior to stimulation‐dependent uptake with botulinum neurotoxin F utilising the three isoforms of SV2 as second receptor

Andreas Rummel, Kirstin Häfner, Stefan Mahrhold, +7

Journal of Neurochemistry

High ToxicitySynaptic TransmissionImmunologyBotulinum Neurotoxins CSynaptic Signaling +16

Two Carbohydrate Binding Sites in the HCC-domain of Tetanus Neurotoxin are Required for Toxicity

Andreas Rummel, Steffen Bade, Jürgen Alves, +2

Journal of Molecular Biology

Carbohydrate Binding SitesToxinologyBiochemistryMedicineToxicology +4

Botulinum toxin A and the cutaneous nociception in humans: A prospective, double-blind, placebo-controlled, randomized study

Wendelin Blersch, Wilhelm Schulte‐Mattler, Saskia Przywara, +3

Journal of the Neurological Sciences

Pain SyndromeInterventional Pain MedicineHealth SciencesPain MedicineBotulinum Toxin A +6

Botulinum A toxins: units versus units

Kai Wohlfarth, Hilke Göschel, Jürgen Frevert, +2

Naunyn-Schmiedeberg s Archives of Pharmacology

Microbial ToxinToxinologyToxicologyMicrobiologyPlant Toxin +1

Botulinum neurotoxin type D enables cytosolic delivery of enzymatically active cargo proteins to neurones via unfolded translocation intermediates

Steffen Bade, Andreas Rummel, Clemens Reisinger, +4

Journal of Neurochemistry