Hitoshi Sawa

WRM-1 Activates the LIT-1 Protein Kinase to Transduce Anterior/Posterior Polarity Signals in C. elegans

Christian E. Rocheleau, Jun Yasuda, Tae Ho Shin et al. · Cell · 1999 · 277 citations · Full text

Signal Transduction, Developmental Biology, Signaling Pathway +10

The Caenorhabditis elegans gene lin-17, which is required for certain asymmetric cell divisions, encodes a putative seven-transmembrane protein similar to the Drosophila frizzled protein.

Hitoshi Sawa, Leslie Lobel, H. Robert Horvitz · Genes & Development · 1996 · 216 citations · Full text

Molecular Genetics, Cellular Physiology, Signaling Pathway +18

Evidence for a base-pairing interaction between U6 small nuclear RNA and 5' splice site during the splicing reaction in yeast.

Hitoshi Sawa, John Abelson · Proceedings of the National Academy of Sciences · 1992 · 167 citations · Full text

Genetics, Rna Splicing, Molecular Biology +17

Wnt Signals Can Function as Positional Cues in Establishing Cell Polarity

Bob Goldstein, Hisako Takeshita, Kota Mizumoto et al. · Developmental Cell · 2006 · 165 citations · Full text

Optogenetics, Developmental Biology, Signal Transduction +13

A β-Catenin Identified by Functional Rather Than Sequence Criteria and Its Role in Wnt/MAPK Signaling

Ambrose R. Kidd, Jennifer A. Miskowski, Kellee R. Siegfried et al. · Cell · 2005 · 147 citations · Full text

Systems Biology, Signal Transduction, Molecular Physiology +9