Thymine DNA Glycosylase Is Essential for Active DNA Demethylation by Linked Deamination-Base Excision Repair

Salvatore Cortellino, Jinfei Xu, Mara Sannai, +21

Cell

ChromatinGenome InstabilityNatural SciencesDna AnalysisOligonucleotide +9

Defective ciliogenesis, embryonic lethality and severe impairment of the Sonic Hedgehog pathway caused by inactivation of the mouse complex A intraflagellar transport gene Ift122/Wdr10, partially overlapping with the DNA repair gene Med1/Mbd4

Salvatore Cortellino, Chengbing Wang, Baolin Wang, +9

Developmental Biology

Knockout MouseGenome InstabilityCell LineageDevelopmental BiologyEmbryonic Lethality +7

CD8+ T Cells Complement Antibodies in Protecting against Yellow Fever Virus

Maria Rosaria Bassi, Michael Kongsgaard, Maria Abildgaard Steffensen, +8

The Journal of Immunology

Humoral ResponseImmunologyImmunologic MechanismAntigen ProcessingImmunotherapy +14

Matrix metalloproteinase-8 overexpression prevents proper tissue repair

Patricia L. Danielsen, Anders Vedel Holst, Henrik R. Maltesen, +8

Surgery

FibrosisCell-matrix InteractionWound HealingMatrix BiologyMedicine +3

Transgenic Rescue of Adipocyte Glucose-dependent Insulinotropic Polypeptide Receptor Expression Restores High Fat Diet-induced Body Weight Gain

Randi Ugleholdt, Jens Pedersen, Maria Rosaria Bassi, +10

Journal of Biological Chemistry

Adaptive immune responses to booster vaccination against yellow fever virus are much reduced compared to those after primary vaccination

Michael Kongsgaard, Maria Rosaria Bassi, Michael Rasmussen, +7

Scientific Reports

Extinction of Zika Virus and Usutu Virus by Lethal Mutagenesis Reveals Different Patterns of Sensitivity to Three Mutagenic Drugs

Maria Rosaria Bassi, Raquel Navarro Sempere, Prashansa Meyn, +2

Antimicrobial Agents and Chemotherapy

MHC class II invariant chain–adjuvanted viral vectored vaccines enhances T cell responses in humans

Ilaria Esposito, Paola Cicconi, Anna Morena D’Alise, +50

Science Translational Medicine

Pre-Existing Vector Immunity Does Not Prevent Replication Deficient Adenovirus from Inducing Efficient CD8 T-Cell Memory and Recall Responses

Maria Abildgaard Steffensen, Benjamin A. H. Jensen, Peter Johannes Holst, +3

PLoS ONE

Viral ReplicationAdenoviral VectorImmunologyAntigen ProcessingCd4 T Cell Responses +15

Vaccination with Replication Deficient Adenovectors Encoding YF-17D Antigens Induces Long-Lasting Protection from Severe Yellow Fever Virus Infection in Mice

Maria Rosaria Bassi, Mads A. B. Larsen, Michael Kongsgaard, +5

PLoS neglected tropical diseases

Yf VaccineImmunologyViral PathogenesisImmunotherapyVaccine Target +14