Sec6l-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction

Emmanuel J. H. J. Wiertz, Domenico Tortorella, Matthew Bogyo, +5

Nature

Sec6l-mediated TransferProtein SecretionBiochemistryProteasomeEndocytic Pathway +8

Structure and immune recognition of trimeric pre-fusion HIV-1 Env

Marie Pancera, Tongqing Zhou, Aliaksandr Druz, +24

Nature

Human RetrovirusImmunologyAntiviral ResponseVirologyChronic Viral Infection +3

TRIM5 is an innate immune sensor for the retrovirus capsid lattice

Thomas Pertel, Stéphane Hausmann, Damien Morger, +13

Nature

Virus StructureInnate Immune SensorHuman RetrovirusPathogenesisImmunology +6

Video-rate nanoscopy using sCMOS camera–specific single-molecule localization algorithms

Fang Huang, Tobias M.P. Hartwich, Félix Rivera-Molina, +10

Nature Methods

Single Molecule BiophysicsEngineeringMicroscopyVideo-rate NanoscopyBiomedical Imaging +6

Semen-Derived Amyloid Fibrils Drastically Enhance HIV Infection

Jan Münch, Elke Rücker, Ludger Ständker, +18

Cell

Human RetrovirusAntiviral ResponseVirologyProtein MisfoldingHiv +1

Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions

James B. Munro, Jason Gorman, Xiaochu Ma, +9

Science

Conformational DynamicsImmune EvasionVirus StructureViral ReplicationProtein Folding +11

Retroviruses can establish filopodial bridges for efficient cell-to-cell transmission

Nathan M. Sherer, Maik J. Lehmann, Luisa F. Jiménez‐Soto, +3

Nature Cell Biology

Viral ReplicationFilopodial BridgesHuman RetrovirusVirologyGene Vector +2

Visualization of Retroviral Replication in Living Cells Reveals Budding into Multivesicular Bodies

Nathan M. Sherer, Maik J. Lehmann, Luisa F. Jiménez‐Soto, +7

Traffic

Actin- and myosin-driven movement of viruses along filopodia precedes their entry into cells

Maik J. Lehmann, Nathan M. Sherer, Carolyn B. Marks, +2

The Journal of Cell Biology

Viral ReplicationCytoskeletonVirus StructureCellular PhysiologyMyosin-driven Movement +16

Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody

Rui Kong, Kai Xu, Tongqing Zhou, +31

Science