FGF21 treatment ameliorates alcoholic fatty liver through activation of AMPK-SIRT1 pathway

Shenglong Zhu, Lei Ma, Yunzhou Wu, +9

Acta Biochimica et Biophysica Sinica

PathologyFatty Liver DiseaseMetabolic SyndromeNonalcoholic Fatty Liver DiseaseFibroblast Growth Factor +20

FGF21 ameliorates nonalcoholic fatty liver disease by inducing autophagy

Shenglong Zhu, Yunzhou Wu, Xianlong Ye, +7

Molecular and Cellular Biochemistry

Metabolic SyndromeMitophagyCell AutophagyHepatologyLiver Physiology +7

SARS-CoV-2 spike protein causes blood coagulation and thrombosis by competitive binding to heparan sulfate

Yi Zheng, Jinxiang Zhao, Jiaqi Li, +9

International Journal of Biological Macromolecules

ThrombosisBlood PlateletCompetitive BindingPathologyVirology +7

Recombinant Newcastle disease virus (NDV/Anh-IL-2) expressing human IL-2 as a potential candidate for suppresses growth of hepatoma therapy

Yunzhou Wu, Jinjiao He, Ying An, +10

Journal of Pharmacological Sciences

Recombinant Newcastle disease virus expressing human TRAIL as a potential candidate for hepatoma therapy

Yunzhou Wu, Jinjiao He, Jingshu Geng, +7

European Journal of Pharmacology

Potential CandidateHepatologyHepatoma TherapyHistopathologyViral Pathogenesis +7

Pharmacological efficacy of FGF21 analogue, liraglutide and insulin glargine in treatment of type 2 diabetes

Xianlong Ye, Jianying Qi, Dan Yu, +6

Journal of Diabetes and its Complications

Translational MedicineDiabetes ManagementMedicineInsulin GlargineDiabetes +6

The bispecific antibody aimed at the vicious circle of IL-1β and IL-17A, is beneficial for the collagen-induced rheumatoid arthritis of mice through NF-κB signaling pathway

Qiang Wu, Yunxin Wang, Qiuying Wang, +9

Immunology Letters

ImmunologyImmune RegulationImmune SystemInflammationRheumatoid Disorder +14

FGF21 exerts comparable pharmacological efficacy with Adalimumab in ameliorating collagen-induced rheumatoid arthritis by regulating systematic inflammatory response

Dan Yu, Xianlong Ye, Ruixiang Che, +8

Biomedicine & Pharmacotherapy

InflammationRheumatologyRheumatoid DisorderAnti-inflammatoryAutoimmune Disease +13

Fibroblast growth factor 21 alleviates idiopathic pulmonary fibrosis by inhibiting PI3K-AKT-mTOR signaling and stimulating autophagy

Jianying Qi, Yuanyuan Wu, Zhimou Guo, +5

International Journal of Biological Macromolecules

InflammationAntifibrotic TherapyFibrosisInflammatory Lung DiseaseAdvanced Lung Disease +11

Enhancement of the Pharmacological Efficacy of FGF-21 by Genetic Modification and PEGylation

Xianlong Ye, Jianying Qi, Guopeng Sun, +7

Current Pharmaceutical Biotechnology