Alexandre S. Lawrenson

Generation of quinolone antimalarials targeting the <i>Plasmodium falciparum</i> mitochondrial respiratory chain for the treatment and prophylaxis of malaria

Giancarlo A. Biagini, Nicholas Fisher, Alison E. Shone et al. · Proceedings of the National Academy of Sciences · 2012 · 156 citations

Antimalarial 4(1H)-pyridones bind to the Q _i site of cytochrome <i>bc</i> ₁

Michael J. Capper, Paul M. O’Neill, Nicholas Fisher et al. · Proceedings of the National Academy of Sciences · 2015 · 95 citations · Full text

Cytochrome b Mutation Y268S Conferring Atovaquone Resistance Phenotype in Malaria Parasite Results in Reduced Parasite bc1 Catalytic Turnover and Protein Expression

Nicholas Fisher, Roslaini Abd Majid, Thomas Antoine et al. · Journal of Biological Chemistry · 2012 · 92 citations · Full text

Mitochondrial Cytochrome Bc, Antiparasitic Agent, Genetics +20

HDQ, a Potent Inhibitor of Plasmodium falciparum Proliferation, Binds to the Quinone Reduction Site of the Cytochrome <i>bc</i> ₁ Complex

Cindy Vallières, Nicholas Fisher, Thomas Antoine et al. · Antimicrobial Agents and Chemotherapy · 2012 · 59 citations · Full text

Potent Inhibitor, Antiparasitic Agent, Malaria +20

Thiazolides as Novel Antiviral Agents. 2. Inhibition of Hepatitis C Virus Replication

Andrew V. Stachulski, Chandrakala Pidathala, Eleanor C. Row et al. · Journal of Medicinal Chemistry · 2011 · 47 citations