LptE binds to and alters the physical state of LPS to catalyze its assembly at the cell surface

G. Malojcic, Dorothee Andres, Marcin Grabowicz, +4

Proceedings of the National Academy of Sciences

A Peptidomimetic Antibiotic Interacts with the Periplasmic Domain of LptD from <i>Pseudomonas aeruginosa</i>

Gloria Andolina, László Csaba Bencze, Katja Zerbe, +9

ACS Chemical Biology

Structural Basis of Substrate Specificity of Human Oligosaccharyl Transferase Subunit N33/Tusc3 and Its Role in Regulating Protein N-Glycosylation

Elisabeth Mohorko, Robin L. Owen, G. Malojcic, +3

Structure

Signal TransductionCellular EnzymologyBiochemistryNatural SciencesSubstrate Specificity +8

Selective inhibition of CDK7 reveals high-confidence targets and new models for TFIIH function in transcription

Jenna K. Rimel, Zachary C. Poss, Benjamin Erickson, +26

Genes & Development

DsbL and DsbI Form a Specific Dithiol Oxidase System for Periplasmic Arylsulfate Sulfotransferase in Uropathogenic Escherichia coli

John P.A. Grimshaw, Christian U. Stirnimann, Maurice S. Brozzo, +4

Journal of Molecular Biology

BiosynthesisEngineeringCellular EnzymologyBiochemistryBiotransformation +8

Discovery of SY-5609: A Selective, Noncovalent Inhibitor of CDK7

Jason Marineau, Kristin B. Hamman, Shanhu Hu, +16

Journal of Medicinal Chemistry

Structural basis of TRPC4 regulation by calmodulin and pharmacological agents

Deivanayagabarathy Vinayagam, Dennis Quentin, Jing Yu-Strzelczyk, +9

eLife

A structural and biochemical basis for PAPS-independent sulfuryl transfer by aryl sulfotransferase from uropathogenic <i>Escherichia coli</i>

G. Malojcic, Robin L. Owen, John P.A. Grimshaw, +3

Proceedings of the National Academy of Sciences

Crystal StructureBiosynthesisBiotransformationBiochemistryPaps-independent Sulfuryl Transfer +12

Discovery of a Potent and Selective TRPC5 Inhibitor, Efficacious in a Focal Segmental Glomerulosclerosis Model

Maolin Yu, Mark W. Ledeboer, Matthew H. Daniels, +9

ACS Medicinal Chemistry Letters

A novel bis-phenanthridine triamine with pH controlled binding to nucleotides and nucleic acids

G. Malojcic, Ivo Piantanida, Mirna Marinić, +5

Organic & Biomolecular Chemistry

Novel Bis-phenanthridine TriamineBioorganic ChemistryMolecular BiologyPhenanthridine SubunitsChemical Biology +14