Force generation by skeletal muscle is controlled by mechanosensing in myosin filaments

Marco Linari, Elisabetta Brunello, Massimo Reconditi, +6

Nature

MechanobiologyMuscle FunctionEngineeringSkeletal MusclePhysiology +11

Skeletal Muscle Performance Determined by Modulation of Number of Myosin Motors Rather Than Motor Force or Stroke Size

Gabriella Piazzesi, Massimo Reconditi, Marco Linari, +9

Cell

MechanobiologyMuscle PhysiologyMuscle FunctionKinesiologyHealth Sciences +12

The myosin motor in muscle generates a smaller and slower working stroke at higher load

Massimo Reconditi, Marco Linari, L Lucii, +9

Nature

Muscle FunctionKinesiologyMuscle InjurySkeletal MuscleMuscle Generates +10

The Stiffness of Skeletal Muscle in Isometric Contraction and Rigor: The Fraction of Myosin Heads Bound to Actin

Marco Linari, Ian M. Dobbie, Massimo Reconditi, +4

Biophysical Journal

MechanobiologyMuscle FunctionKinesiologyEngineeringMuscle Injury +9

Elastic bending and active tilting of myosin heads during muscle contraction

Ian M. Dobbie, Marco Linari, Gabriella Piazzesi, +5

Nature

MechanobiologyMuscle PhysiologyMuscle FunctionKinesiologyEngineering +9

Mechanism of force generation by myosin heads in skeletal muscle

Gabriella Piazzesi, Massimo Reconditi, Marco Linari, +6

Nature

MechanobiologyMuscle FunctionKinesiologyEngineeringSkeletal Muscle +7

Myosin filament activation in the heart is tuned to the mechanical task

Massimo Reconditi, Marco Caremani, Francesca Pinzauti, +6

Proceedings of the National Academy of Sciences

Interference fine structure and sarcomere length dependence of the axial x-ray pattern from active single muscle fibers

Marco Linari, Gabriella Piazzesi, Ian M. Dobbie, +6

Proceedings of the National Academy of Sciences

Skeletal muscle resists stretch by rapid binding of the second motor domain of myosin to actin

Elisabetta Brunello, Massimo Reconditi, Ravikrishnan Elangovan, +7

Proceedings of the National Academy of Sciences

Second Motor DomainMuscle FunctionEngineeringCytoskeletonMechanotransduction +17

Temperature dependence of the force‐generating process in single fibres from frog skeletal muscle

Gabriella Piazzesi, Massimo Reconditi, Natalia A. Koubassova, +4

The Journal of Physiology