Jan Dreher

Identification of 2-Anilino-9-methoxy-5,7-dihydro-6<i>H</i>-pyrimido[5,4-<i>d</i>][1]benzazepin-6-ones as Dual PLK1/VEGF-R2 Kinase Inhibitor Chemotypes by Structure-Based Lead Generation

Anne‐Marie Egert‐Schmidt, Jan Dreher, Ute Dunkel et al. · Journal of Medicinal Chemistry · 2010 · 66 citations · Full text

Bioorganic Chemistry, Kinase Inhibitors, Lead Identification +17

2-Anilino-4-(benzimidazol-2-yl)pyrimidines – A multikinase inhibitor scaffold with antiproliferative activity toward cancer cell lines

Renate Determann, Jan Dreher, Knut Baumann et al. · European Journal of Medicinal Chemistry · 2012 · 50 citations · Full text

Cancer Cell Lines, Antiproliferative Activity, Medicine +7

xMaP—An Interpretable Alignment-Free Four-Dimensional Quantitative Structure–Activity Relationship Technique Based on Molecular Surface Properties and Conformer Ensembles

Jan Dreher, Josef Scheiber, Nikolaus Stiefl et al. · Journal of Chemical Information and Modeling · 2017 · 15 citations

Structural Bioinformatics, Biomolecular Structure Prediction, Molecular Biology +17

QSAR guided synthesis of simplified antiplasmodial analogs of naphthylisoquinoline alkaloids

Gerhard Bringmann, Sebastian Bischof, Steffen Müller et al. · European Journal of Medicinal Chemistry · 2010 · 10 citations

Combinatorial Chemistry, Medicine, Organic Chemistry +6