Tyler Mandt

Coupling endonucleases with DNA end–processing enzymes to drive gene disruption

Michael T. Certo, Kamila Gwiazda, Ryan Kuhar et al. · Nature Methods · 2012 · 107 citations

Life Sciences, Genetics, Molecular Biology +14

Time-restricted feeding normalizes hyperinsulinemia to inhibit breast cancer in obese postmenopausal mouse models

Manasi Das, Lesley G. Ellies, Deepak Kumar et al. · Nature Communications · 2021 · 89 citations · Full text

Medicine, Endocrinology, Oncology +17

Novel fluorescent genome editing reporters for monitoring DNA repair pathway utilization at endonuclease-induced breaks

Ryan Kuhar, Kamila Gwiazda, Olivier Humbert et al. · Nucleic Acids Research · 2013 · 70 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

SLC41A1 Mg2+ transport is regulated via Mg2+-dependent endosomal recycling through its N-terminal cytoplasmic domain

Tyler Mandt, Yumei Song, Andrew M. Scharenberg et al. · Biochemical Journal · 2011 · 48 citations

Life Sciences, Biochemistry, Molecular Biology +14

Treatment of Hepatocellular Carcinoma by Multimodal In Situ Vaccination Using Cryoablation and a Plant Virus Immunostimulant

Mansur A. Ghani, Amandip Bangar, Yunpeng Yang et al. · Journal of Vascular and Interventional Radiology · 2023 · 12 citations · Full text

Medicine, Immunology, Oncology +17