Andrew Grimshaw

A naturally occurring variant of the human prion protein completely prevents prion disease

Emmanuel A. Asante, Michelle Smidak, Andrew Grimshaw et al. · Nature · 2015 · 201 citations · Full text

Creutzfeldt-jakob Disease, Human Prion Protein, Medicine +6

Absence of spontaneous disease and comparative prion susceptibility of transgenic mice expressing mutant human prion proteins

Emmanuel A. Asante, Ian Gowland, Andrew Grimshaw et al. · Journal of General Virology · 2009 · 66 citations · Full text

Inherited Prion Disease A117V Is Not Simply a Proteinopathy but Produces Prions Transmissible to Transgenic Mice Expressing Homologous Prion Protein

Emmanuel A. Asante, Jacqueline M. Linehan, Michelle Smidak et al. · PLoS Pathogens · 2013 · 50 citations · Full text

Creutzfeldt-jakob Disease, Genetics, Produces Prions Transmissible +16

Transmission Properties of Human PrP 102L Prions Challenge the Relevance of Mouse Models of GSS

Emmanuel A. Asante, Andrew Grimshaw, Michelle Smidak et al. · PLoS Pathogens · 2015 · 27 citations · Full text

Knockout Mouse, Signal Transduction, Prions Challenge +14

Spontaneous generation of prions and transmissible PrP amyloid in a humanised transgenic mouse model of A117V GSS

Emmanuel A. Asante, Jacqueline M. Linehan, Andrew Tomlinson et al. · PLoS Biology · 2020 · 25 citations · Full text

Inherited Prion Disease, Creutzfeldt-jakob Disease, Genetics +22