Pengqin Chen

Development of 2-amino-4-phenylthiazole analogues to disrupt myeloid differentiation factor 88 and prevent inflammatory responses in acute lung injury

Lingfeng Chen, Hongjin Chen, Pengqin Chen et al. · European Journal of Medicinal Chemistry · 2018 · 58 citations · Full text

Acute Lung Injury, Inflammation, Cytokine +10

Discovery of caffeic acid phenethyl ester derivatives as novel myeloid differentiation protein 2 inhibitors for treatment of acute lung injury

Lingfeng Chen, Yiyi Jin, Hongjin Chen et al. · European Journal of Medicinal Chemistry · 2017 · 41 citations · Full text

Acute Lung Injury, Biochemistry, Medicine +6

Pharmacological inhibition of MyD88 suppresses inflammation in tubular epithelial cells and prevents diabetic nephropathy in experimental mice

Qiuyan Zhang, Sujing Xu, Jianchang Qian et al. · Acta Pharmacologica Sinica · 2021 · 27 citations · Full text

Inflammation, Experimental Mice, Renal Function +13

Design, synthesis and biological evaluation of 7H-pyrrolo[2,3-d]pyrimidine derivatives containing 1,8-naphthyridine-4-one fragment

Jianqing Zhang, Pengqin Chen, Yongli Duan et al. · European Journal of Medicinal Chemistry · 2021 · 18 citations

Combinatorial Chemistry, Derivatives, Bioorganic Chemistry +7

Discovery of N-(3-bromo-1H-indol-5-yl)-quinazolin-4-amine as an effective molecular skeleton to develop reversible/irreversible pan-HER inhibitors

Qidong Tang, Ting Peng, Jie Hu et al. · European Journal of Medicinal Chemistry · 2022 · 13 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Effective Molecular Skeleton +10