Use of the CRISPR/Cas9 System to Produce Genetically Engineered Pigs from In Vitro-Derived Oocytes and Embryos1

Kristin M. Whitworth, Kiho Lee, Joshua A. Benne, +13

Biology of Reproduction

EngineeringGeneticsPig GenomeVitro-derived OocytesCrispr/cas9 System +14

New perspective on conceptus estrogens in maternal recognition and pregnancy establishment in the pig†

Ashley E. Meyer, Caroline A Pfeiffer, Kelsey E. Brooks, +14

Biology of Reproduction

Zygote injection of CRISPR/Cas9 RNA successfully modifies the target gene without delaying blastocyst development or altering the sex ratio in pigs

Kristin M. Whitworth, Joshua A. Benne, Lee D. Spate, +7

Transgenic Research

Developmental BiologyTarget GeneGeneticsGenetic EngineeringZygote Injection +9

<i>NANOG</i> is required to form the epiblast and maintain pluripotency in the bovine embryo

M. S. Ortega, Andrew M. Kelleher, Eleanore V. O’Neil, +3

Molecular Reproduction and Development

Inactivation of porcine interleukin-1β results in failure of rapid conceptus elongation

Jeffrey J. Whyte, Ashley E. Meyer, Lee D. Spate, +6

Proceedings of the National Academy of Sciences

A porcine model of phenylketonuria generated by CRISPR/Cas9 genome editing

Erik Koppes, Bethany K. Redel, Marie A. Johnson, +23

JCI Insight

Generation of a Commercial-Scale Founder Population of Porcine Reproductive and Respiratory Syndrome Virus Resistant Pigs Using CRISPR-Cas

Brian T. Burger, Benjamin P. Beaton, Matthew A. Campbell, +34

The CRISPR Journal

Elite Porcine LinesGenome SurgeryGeneticsPathogenesisGenetic Engineering +11

Ablation of conceptus PTGS2 expression does not alter early conceptus development and establishment of pregnancy in the pig†

Caroline A Pfeiffer, Ashley E. Meyer, Kelsey E. Brooks, +13

Biology of Reproduction

FertilityPtgs2+/+ ConceptusesGeneticsPtgs2-/- ConceptusReproductive Biology +17

Zygote injection of RNA encoding Cre recombinase results in efficient removal of LoxP flanked neomycin cassettes in pigs

Kristin M. Whitworth, Raissa F. Cecil, Joshua A. Benne, +5

Transgenic Research

Improvement of in vitro and early in utero porcine clone development after somatic donor cells are cultured under hypoxia

Bethany R. Mordhorst, Joshua A. Benne, Raissa F. Cecil, +7

Molecular Reproduction and Development