A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3

Ian PM Tomlinson, Emily L. Webb, Luis G. Carvajal‐Carmona, +71

Nature Genetics

Cancer SusceptibilityGenome-wide Association StudyChromosomes 10P14MedicineGenetics +8

A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk

Peter Broderick, Luis G. Carvajal‐Carmona, Alan Pittman, +27

Nature Genetics

Genome-wide Association StudyCancer RiskGeneticsGenetic EpidemiologyCommon Alleles +6

Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13.3 influence colorectal cancer risk

Emma Jaeger, Emily L. Webb, Kimberley Howarth, +29

Nature Genetics

Cancer RiskChromosome 15Q13.3MedicineGeneticsGenetic Epidemiology +6

The colorectal cancer risk at 18q21 is caused by a novel variant altering <i>SMAD7</i> expression

Alan Pittman, Silvia Naranjo, Emily L. Webb, +11

Genome Research

GeneticsPathologyCancer BiologyTumor BiologyOncology +17

Allelic Variation at the 8q23.3 Colorectal Cancer Risk Locus Functions as a Cis-Acting Regulator of EIF3H

Alan Pittman, Silvia Naranjo, Sanni E. Jalava, +17

PLoS Genetics

GeneticsGenetic EpidemiologyPathologyCancer BiologyTumor Biology +14

Search for low penetrance alleles for colorectal cancer through a scan of 1467 non-synonymous SNPs in 2575 cases and 2707 controls with validation by kin-cohort analysis of 14 704 first-degree relatives

Emily L. Webb, Matthew Rudd, Gabrielle S. Sellick, +12

Human Molecular Genetics

Refinement of the basis and impact of common 11q23.1 variation to the risk of developing colorectal cancer

Alan Pittman, Emily L. Webb, Luis G. Carvajal‐Carmona, +60

Human Molecular Genetics

Ld MappingCancer RiskCancer EpidemiologyMedicineGenetics +12

Polymorphisms in the cytochrome P450 genes CYP1A2, CYP1B1, CYP3A4, CYP3A5, CYP11A1, CYP17A1, CYP19A1and colorectal cancer risk

Lara Bethke, Emily L. Webb, Gabrielle S. Sellick, +4

BMC Cancer

Evaluation of germline BMP4 mutation as a cause of colorectal cancer

Steven Lubbe, Alan Pittman, C. Matijssen, +9

Human Mutation

GeneticsPathologyBmp4 Causes CrcTumor BiologyBmp4 Function +14

Genetic variation in CXCR4 and risk of chronic lymphocytic leukemia

Dalemari Crowther-Swanepoel, Mobshra Qureshi, Martin J.S. Dyer, +4

Blood