Yishi Shen

Atherosclerosis-associated hepatic secretion of VLDL but not PCSK9 is dependent on cargo receptor protein Surf4

Bingxiang Wang, Yishi Shen, Lei Zhai et al. · Journal of Lipid Research · 2021 · 39 citations · Full text

Surf4 regulates expression of proprotein convertase subtilisin/kexin type 9 (PCSK9) but is not required for PCSK9 secretion in cultured human hepatocytes

Yishi Shen, Bingxiang Wang, Shijun Deng et al. · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 2019 · 36 citations

Protein Function, Signaling Pathway, Protein Expression +12

The role of the C-terminal domain of PCSK9 and SEC24 isoforms in PCSK9 secretion

Shijun Deng, Yishi Shen, Hongmei Gu et al. · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 2020 · 32 citations

Protein Secretion, Signal Transduction, Molecular Physiology +9

The role of hepatic Surf4 in lipoprotein metabolism and the development of atherosclerosis in apoE−/− mice

Yishi Shen, Hongmei Gu, Lei Zhai et al. · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 2022 · 24 citations

Inflammation, Lipid Synthesis, Biochemistry +10

Surf4 (Surfeit Locus Protein 4) Deficiency Reduces Intestinal Lipid Absorption and Secretion and Decreases Metabolism in Mice

Geru Tao, Hao Wang, Yishi Shen et al. · Arteriosclerosis Thrombosis and Vascular Biology · 2023 · 19 citations · Full text