Comprehensive mutational analysis of primary and relapse acute promyelocytic leukemia

Vikas Madan, Pavithra Shyamsunder, Lin Han, +49

Leukemia

Detection of minimal residual disease following induction immunochemotherapy predicts progression free survival in mantle cell lymphoma: final results of CALGB 59909

Hui Liu, Jeffrey L. Johnson, Greg Koval, +8

Haematologica

Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia

Houda Alachkar, Martin Mutonga, Klaus H. Metzeler, +9

Oncotarget

Expression and polymorphism (rs4880) of mitochondrial superoxide dismutase (SOD2) and asparaginase induced hepatotoxicity in adult patients with acute lymphoblastic leukemia

Houda Alachkar, Noreen Fulton, B Sanford, +7

The Pharmacogenomics Journal

Asparaginase Induced HepatotoxicityHematologyAcute Lymphoblastic LeukemiaPathologyCell Death +5

Excessive collagen accumulation in dystrophic (mdx) respiratory musculature is independent of enhanced activation of the NF-κB pathway

Katie Graham, Rajvir Singh, Gregory Millman, +7

Journal of the Neurological Sciences

InflammationFibrosisInflammatory DiseaseImmunologyRespiratory Musculature +10

WT1 peptide vaccine in Montanide in contrast to poly ICLC, is able to induce WT1-specific immune response with TCR clonal enrichment in myeloid leukemia

Hongtao Liu, Yuanyuan Zha, Noura J. Choudhury, +10

Experimental Hematology and Oncology

Inhibition of insulin‐like growth factor 1 receptor enhances the efficacy of sorafenib in inhibiting hepatocellular carcinoma cell growth and survival

Fang Wang, Thomas Bank, Gregory Malnassy, +9

Hepatology Communications

T-LAK cell-originated protein kinase presents a novel therapeutic target in<i>FLT3</i>-ITD mutated acute myeloid leukemia

Houda Alachkar, Martin Mutonga, Gregory Malnassy, +12

Oncotarget

Targeting Suppressor of Variegation 3-9 Homologue 2 (SUV39H2) in Acute Lymphoblastic Leukemia (ALL)

Martin Mutonga, Kenji Tamura, Gregory Malnassy, +6

Translational Oncology

Histone ModificationsMixed-phenotype Acute LeukemiaEpigenetic ChangeImmunologySuv39h2 Mrna +15

A phase I and pharmacodynamic study of the histone deacetylase inhibitor belinostat plus azacitidine in advanced myeloid neoplasia

Olatoyosi Odenike, Anna B. Halpern, Lucy A. Godley, +12

Investigational New Drugs

Hematological MalignancyPharmacodynamic StudyOncologyMedicineMixed-phenotype Acute Leukemia +8