The immunoglobulin superfamily protein Izumo is required for sperm to fuse with eggs

Naokazu Inoue, Masahito Ikawa, Ayako Isotani, +1

Nature

InfertilityFertilityProtein IzumoGeneticsImmunology +7

Generation of mutant mice by pronuclear injection of circular plasmid expressing Cas9 and single guided RNA

Daisuke Mashiko, Yoshitaka Fujihara, Yuhkoh Satouh, +3

Scientific Reports

SPACA1-deficient male mice are infertile with abnormally shaped sperm heads reminiscent of globozoospermia

Yoshitaka Fujihara, Yuhkoh Satouh, Naokazu Inoue, +3

Development

SpermatogenesisFertilityGeneticsSemen AnalysisReproductive Biology +16

Sperm calcineurin inhibition prevents mouse fertility with implications for male contraceptive

Haruhiko Miyata, Yuhkoh Satouh, Daisuke Mashiko, +7

Science

Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice

Haruhiko Miyata, Julio M Castaneda, Yoshitaka Fujihara, +18

Proceedings of the National Academy of Sciences

SpermatogenesisFertilityGeneticsReproductive BiologyEpigenetics +22

Disruption of ADAM3 Impairs the Migration of Sperm into Oviduct in Mouse1

Ryo Yamaguchi, Yuko Muro, Ayako Isotani, +5

Biology of Reproduction

FertilityGeneticsReproductive BiologyFertilisationEmbryology +15

Comparison of Gene Expression in Male and Female Mouse Blastocysts Revealed Imprinting of the X-Linked Gene, Rhox5/Pem, at Preimplantation Stages

Shin Kobayashi, Ayako Isotani, Nathan Mise, +8

Current Biology

InfertilityDevelopmental BiologyFertilityGeneticsMorphogenesis +11

Behavior of Mouse Spermatozoa in the Female Reproductive Tract from Soon after Mating to the Beginning of Fertilization1

Yuko Muro, Hidetoshi Hasuwa, Ayako Isotani, +5

Biology of Reproduction

SpermatogenesisFemale Reproductive TractFertilityGeneticsReproductive Health +22

FISH Analysis of 142 EGFP Transgene Integration Sites into the Mouse Genome

Tomoko Nakanishi, Asato Kuroiwa, Shuichi Yamada, +8

Genomics

Fish AnalysisDevelopmental BiologyTissue DevelopmentGeneticsMolecular Genetics +6

Complementation of placental defects and embryonic lethality by trophoblast-specific lentiviral gene transfer

Yuka Okada, Yuko Ueshin, Ayako Isotani, +10

Nature Biotechnology

XenotransplantationDevelopmental BiologyPlacental DevelopmentEmbryonic LethalityGenetics +7