Jean-François Chiasson

Discovery of 4-{1-[({1-[4-(trifluoromethyl)benzyl]-1H-indol-7-yl}carbonyl)amino]cyclopropyl}benzoic acid (MF-766), a highly potent and selective EP4 antagonist for treating inflammatory pain

John Colucci, Michael J. Boyd, Carl Berthelette et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 39 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Trisubstituted ureas as potent and selective mPGES-1 inhibitors

Jean-François Chiasson, Louise Boulet, Christine Brideau et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 23 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +4

A novel series of potent and selective EP4 receptor ligands: Facile modulation of agonism and antagonism

Michael J. Boyd, Carl Berthelette, Jean-François Chiasson et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 20 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16