Therapeutic blockade of PD-L1 and LAG-3 rapidly clears established blood-stage Plasmodium infection

Noah S. Butler, Jacqueline Moebius, Lecia L. Pewe, +6

Nature Immunology

MalariaImmunologyBlood-stage Plasmodium InfectionTherapeutic BlockadeImmunotherapy +2

Lipopolysaccharide Induces Rac1-dependent Reactive Oxygen Species Formation and Coordinates Tumor Necrosis Factor-α Secretion through IKK Regulation of NF-κB

Salih Şanlıoğlu, Carl M. Williams, Lobelia Samavati, +7

Journal of Biological Chemistry

Chronic Exposure to <i>Plasmodium falciparum</i> Is Associated with Phenotypic Evidence of B and T Cell Exhaustion

Joseph J. Illingworth, Noah S. Butler, Sophie Roetynck, +6

The Journal of Immunology

T CellsPathogenesisImmunologyMalariaPhenotypic Evidence +9

Respiratory Syncytial Virus Up-regulates TLR4 and Sensitizes Airway Epithelial Cells to Endotoxin

Martha M. Monick, Timur O. Yarovinsky, Linda S. Powers, +4

Journal of Biological Chemistry

Interleukin-10 Directly Inhibits CD8+ T Cell Function by Enhancing N-Glycan Branching to Decrease Antigen Sensitivity

Logan K. Smith, Giselle M. Boukhaled, Stephanie A. Condotta, +8

Immunity

InflammationDecrease Antigen SensitivityAutoimmune DiseaseT-regulatory CellImmunology +8

Memory CD8 T cell responses exceeding a large but definable threshold provide long-term immunity to malaria

Nathan W. Schmidt, Rebecca Podyminogin, Noah S. Butler, +11

Proceedings of the National Academy of Sciences

Superior Antimalarial Immunity after Vaccination with Late Liver Stage-Arresting Genetically Attenuated Parasites

Noah S. Butler, Nathan W. Schmidt, Ashley M. Vaughan, +3

Cell Host & Microbe

VaccinationSuperior Antimalarial ImmunityMalariaImmunologyParasite Control +4

Extreme CD8 T Cell Requirements for Anti-Malarial Liver-Stage Immunity following Immunization with Radiation Attenuated Sporozoites

Nathan W. Schmidt, Noah S. Butler, Vladimir P. Badovinac, +1

PLoS Pathogens

Adaptive Immune SystemMalariaImmunologyRadiation-attenuated Plasmodium SporozoitesImmunodominance +14

Regulatory T cells impede acute and long-term immunity to blood-stage malaria through CTLA-4

Samarchith P. Kurup, Nyamekye Obeng-Adjei, Scott M. Anthony, +5

Nature Medicine

Autoimmune DiseaseT-regulatory CellHematologyImmune RegulationImmunology +8

Role of Repeated Lung Injury and Genetic Background in Bleomycin-Induced Fibrosis

Man Pyo Chung, Martha M. Monick, Nabeel Hamzeh, +3

American Journal of Respiratory Cell and Molecular Biology