First-in-human study of LY3039478, an oral Notch signaling inhibitor in advanced or metastatic cancer

Christophe Massard, A. Ázaro, Jean‐Charles Soria, +10

Annals of Oncology

Phase II study of gemcitabine as first-line chemotherapy in patients with advanced or metastatic breast cancer

K. Possinger, M. Kaufmann, Robert Coleman, +4

Anti-Cancer Drugs

Promoter methylation of RASSF1A, RARβ and DAPK predict poor prognosis of patients with malignant mesothelioma

Jürgen R. Fischer, U. Ohnmacht, Norman Rieger, +6

Lung Cancer

Malignant DiseaseMalignant MesotheliomaMedicinePathologyCancer Genomics +7

Prognostic significance of RASSF1A promoter methylation on survival of non-small cell lung cancer patients treated with gemcitabine

Jürgen R. Fischer, U. Ohnmacht, Norman Rieger, +4

Lung Cancer

MedicinePathologyCancer GenomicsBronchial NeoplasmPrognostic Significance +5

Preclinical analyses and phase I evaluation of LY2603618 administered in combination with Pemetrexed and cisplatin in patients with advanced cancer

Emiliano Calvo, Victor J. Chen, Mark S. Marshall, +15

Investigational New Drugs

Advanced CancerMedicinePharmacologyAnti-cancer AgentCancer Treatment +4

A first-in-human phase I trial of LY2780301, a dual p70 S6 kinase and Akt Inhibitor, in patients with advanced or metastatic cancer

Analía Azaro, Jordi Rodón, Antonio Calles, +11

Investigational New Drugs

Akt InhibitorFirst-in-human PhaseMedicinePathologyImmune Checkpoint Inhibitor +4

Notch pathway inhibition with LY3039478 in soft tissue sarcoma and gastrointestinal stromal tumours

Olivier Mir, Analía Azaro, Jaime R. Merchan, +12

European Journal of Cancer

Soft Tissue SarcomaMedicineNotch Pathway InhibitionPathologyCancer Biology +6

Gemcitabine plus dose-escalated epirubicin in advanced breast cancer: results of a phase I study

Diana Lüftner, Bernd Flath, C. Akrivakis, +4

Investigational New Drugs

Advanced Breast CancerBreast OncologyOncologyDose-escalated EpirubicinPharmacology +5

A phase II trial of pemetrexed in patients with metastatic renal cancer

R. Thödtmann, Thilo Sauter, S. Weinknecht, +3

Investigational New Drugs

UrologyPhase Ii TrialMetastatic Renal CancerGenitourinary CancerMedicine +5

Antidepressant Drug Use: Differences between Psychiatrists and General Practitioners

Regina Dittmann, Michael Linden, M. Osterheider, +3

Pharmacopsychiatry

Psychotropic MedicationPsychopharmacologyPharmacotherapyMental HealthSocial Sciences +17