Xaver Borer

The Role of Water Molecules in the Structure-Based Design of (5-Hydroxynorvaline)-2-cyclosporin: Synthesis, Biological Activity, and Crystallographic Analysis with Cyclophilin A

Vincent Mikol, Christos Papageorgiou, Xaver Borer · Journal of Medicinal Chemistry · 1995 · 75 citations · Full text

Combinatorial Chemistry, Crystal Structure, Protein Assembly +19

Calcineurin has a very tight-binding pocket for the side chain of residue 4 of cyclosporin

Christos Papageorgiou, Xaver Borer, Richard R. French · Bioorganic & Medicinal Chemistry Letters · 1994 · 45 citations

Protein Chemistry, Medicinal Chemistry, Protein Function +12

Acid‐Catalyzed Rearrangements for a Diastereoselective Entry into a New Fused Hexacyclic Heterocycle: (5<i>RS</i>,7a<i>RS</i>,12<i>RS</i>,14a<i>RS</i>,)‐4,5,7a,11,12,14,14a‐octahydro‐5,12‐dimethyl‐diindolo [1,7‐<i>bc</i>: 1′,7′‐<i>gh</i>][2,6] naphthyridine

Christos Papageorgiou, Xaver Borer · Helvetica Chimica Acta · 1988 · 29 citations

Pyrolytic Ring Closure, Engineering, Heterocyclic +12

A non-peptide ligand for the somatostatin receptor having a benzodiazepinone structure

Christos Papageorgiou, Xaver Borer · Bioorganic & Medicinal Chemistry Letters · 1996 · 28 citations

Biochemistry, Medicine, Mechanism Of Action +7

Cell permeability as a parameter for lead generation in the protein Tyrosine kinase inhibition field

Christos Papageorgiou, Gian Camenisch, Xaver Borer · Bioorganic & Medicinal Chemistry Letters · 2001 · 22 citations

Signal Transduction, Biochemistry, Lead Generation +14