Structure of the miniature type V-F CRISPR-Cas effector enzyme

Satoru N. Takeda, Ryoya Nakagawa, Sae Okazaki, +7

Molecular Cell

Molecular BiologyGene EditingGenome EditingOff-target EffectMedicine +2

Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc

Yongchan Lee, Pattama Wiriyasermkul, Chunhuan Jin, +14

Nature Structural & Molecular Biology

Protein SecretionProtein FunctionBiochemistryProtein AssemblyNatural Sciences +8

TMC1 and TMC2 Proteins Are Pore-Forming Subunits of Mechanosensitive Ion Channels

Yanyan Jia, Yimeng Zhao, Tsukasa Kusakizako, +6

Neuron

Structural basis for channel conduction in the pump-like channelrhodopsin ChRmine

Koichiro Kishi, Yoon Seok Kim, Masahiro Fukuda, +24

Cell

Trimer InterfaceMolecular BiologyCytoskeletonOptogeneticsCellular Physiology +17

Cryo-EM structures of the human volume-regulated anion channel LRRC8

Go Kasuya, Takanori Nakane, Takeshi Yokoyama, +16

Nature Structural & Molecular Biology

Biophysical ModelingMolecular PhysiologyCryo-em StructuresPhysiologyIon Channels +6

Structural basis for xenobiotic extrusion by eukaryotic MATE transporter

Hirotake Miyauchi, Satomi Moriyama, Tsukasa Kusakizako, +11

Nature Communications

Cryo-EM structure of the transposon-associated TnpB enzyme

Ryoya Nakagawa, Hisato Hirano, Satoshi N. Omura, +19

Nature

The structure of lipid nanodisc-reconstituted TRPV3 reveals the gating mechanism

H. Shimada, Tsukasa Kusakizako, Thi Hong Dung Nguyen, +4

Nature Structural & Molecular Biology

Proteinlipid InteractionNatural SciencesMolecular BiologyLipid MovementCellular Biochemistry +3

Time-resolved serial femtosecond crystallography reveals early structural changes in channelrhodopsin

Kazumasa Oda, Takashi Nomura, Takanori Nakane, +45

eLife

EngineeringPhotobiologyMolecular BiologyConformational ChangesOptogenetics +15

Structural basis of gating modulation of Kv4 channel complexes

Yoshiaki Kise, Go Kasuya, Hiroyuki Okamoto, +6

Nature