Thomas J. Mangano

Allosteric ligands for the pharmacologically dark receptors GPR68 and GPR65

Xi‐Ping Huang, Joel Karpiak, Wesley K. Kroeze et al. · Nature · 2015 · 287 citations

Medicine, Molecular Biology, Pharmacology +12

Structural basis for Smoothened receptor modulation and chemoresistance to anticancer drugs

Chong Wang, Huixian Wu, Tama Evron et al. · Nature Communications · 2014 · 253 citations · Full text

Medicine, Oncology, Pharmacology +13

Isolation and pharmacological characterization of omega-grammotoxin SIA, a novel peptide inhibitor of neuronal voltage-sensitive calcium channel responses.

Richard A. Lampe, Patricia A. DeFeo, Matt Davison et al. · Molecular Pharmacology · 1993 · 115 citations

Life Sciences, Neuroscience, Pharmacology +17

Identification of Human <i>Ether-à-go-go</i> Related Gene Modulators by Three Screening Platforms in an Academic Drug-Discovery Setting

Xi‐Ping Huang, Thomas J. Mangano, Sandy Hufeisen et al. · Assay and Drug Development Technologies · 2010 · 81 citations · Full text

Medicine, Cardiology, Pharmacology +17

Fat cell adenylate cyclase system. Enhanced inhibition by adenosine and GTP in the hypothyroid rat.

C C Malbon, Peter J. Rapiejko, Thomas J. Mangano · Journal of Biological Chemistry · 1985 · 80 citations · Full text

Life Sciences, Biochemistry, Pharmacology +13