Patrick M. Gubser

Rapid effector function of memory CD8+ T cells requires an immediate-early glycolytic switch

Patrick M. Gubser, Glenn R. Bantug, Leyla Razik et al. · Nature Immunology · 2013 · 492 citations

Signal Transduction, T-regulatory Cell, Immunology +10

Early precursor T cells establish and propagate T cell exhaustion in chronic infection

Daniel T. Utzschneider, Sarah S. Gabriel, David Chisanga et al. · Nature Immunology · 2020 · 305 citations · Full text

Autoimmune Disease, Adaptive Immune System, Pathogenesis +12

Mitochondria-Endoplasmic Reticulum Contact Sites Function as Immunometabolic Hubs that Orchestrate the Rapid Recall Response of Memory CD8+ T Cells

Glenn R. Bantug, Marco Fischer, Jasmin Grählert et al. · Immunity · 2018 · 196 citations · Full text

Signal Transduction, Organelle Dynamic, Cell Organelle +10

Transforming growth factor-β-regulated mTOR activity preserves cellular metabolism to maintain long-term T cell responses in chronic infection

Sarah S. Gabriel, Carlson Tsui, David Chisanga et al. · Immunity · 2021 · 171 citations · Full text

Inflammation, Adaptive Immune System, Chronic Infection +8

Glutaminase inhibition impairs CD8 T cell activation in STK11-/Lkb1-deficient lung cancer

Sarah A. Best, Patrick M. Gubser, Shalini Sethumadhavan et al. · Cell Metabolism · 2022 · 152 citations · Full text

Tumor Biology, Cancer Immunosurveillance, Oncology +14