Accelerated phospholipid degradation and associated membrane dysfunction in irreversible, ischemic liver cell injury

Kenneth R. Chien, Jacki Abrams, Ada Serroni, +2

Journal of Biological Chemistry

HepatologyBiochemistryLiver PhysiologyCell DeathHepatotoxicity +9

Cyclosporin and carnitine prevent the anoxic death of cultured hepatocytes by inhibiting the mitochondrial permeability transition

John G. Pastorino, Jack W. Snyder, Ada Serroni, +2

Journal of Biological Chemistry

Lipid PeroxidationMitochondrial Permeability TransitionCell DeathRedox BiologyOxidative Stress +18

Early, reversible plasma membrane injury in galactosamine-induced liver cell death.

Sherif El-Mofty, M.C. Scrutton, Ada Serroni, +2

PubMed Central

Mechanisms of cell injury in the killing of cultured hepatocytes by bromobenzene.

A Casini, M Giorli, Ruth Hyland, +3

Journal of Biological Chemistry

InflammationHepatologyMedicineLiver PhysiologyCell Death +6

Cellular pool of transient ferric iron, chelatable by deferoxamine and distinct from ferritin, that is involved in oxidative cell injury.

Ronald J. Rothman, Ada Serroni, J L Farber

Molecular Pharmacology

Mitochondrial damage as a mechanism of cell injury in the killing of cultured hepatocytes by tert-butyl hydroperoxide

Naohiko Masaki, Marlene E. Kyle, Ada Serroni, +1

Archives of Biochemistry and Biophysics

Mitochondrial DamageBiochemistryMitochondrial FunctionLiver PhysiologyLipid Peroxidation +11

Induction of the mitochondrial permeability transition mediates the killing of HeLa cells by staurosporine.

Marco Tafani, Dmytro O. Minchenko, Ada Serroni, +1

PubMed

ApoptosisMitochondrial Permeability TransitionCell DeathMitochondrial BiologyHela Cells +18

Oxygen-mediated cell injury in the killing of cultured hepatocytes by acetaminophen

Ronald J. Gerson, Alessandro Casini, Donna Gilfor, +2

Biochemical and Biophysical Research Communications

InflammationHepatologyBiochemistryMedicineLiver Physiology +12

Protein thiol depletion and the killing of cultured hepatocytes by hydrogen peroxide

Marlene E. Kyle, Dai Nakae, Isao Sakaida, +2

Biochemical Pharmacology

InflammationHepatologyBiochemistryLiver PhysiologyLipid Peroxidation +10

The killing of cultured hepatocytes by N-acetyl-p-benzoquinone imine (NAPQI) as a model of the cytotoxicity of acetaminophen

Andrew W. Harman, Marlene E. Kyle, Ada Serroni, +1

Biochemical Pharmacology

HepatologyBiochemistryMedicineLiver PhysiologyToxicology +6