Jinning Hou

Discovery of the First <i>N</i>-Hydroxycinnamamide-Based Histone Deacetylase 1/3 Dual Inhibitors with Potent Oral Antitumor Activity

Xiaoyang Li, Elizabeth S. Inks, Xiaoguang Li et al. · Journal of Medicinal Chemistry · 2014 · 76 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

Selective HDAC inhibitors with potent oral activity against leukemia and colorectal cancer: Design, structure-activity relationship and anti-tumor activity study

Xiaoyang Li, Yingjie Zhang, Yuqi Jiang et al. · European Journal of Medicinal Chemistry · 2017 · 43 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Discovery of BC-01, a novel mutual prodrug (hybrid drug) of ubenimex and fluorouracil as anticancer agent

Yuqi Jiang, Xiaoyang Li, Jinning Hou et al. · European Journal of Medicinal Chemistry · 2016 · 26 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Histone Deacetylase Inhibitors with Enhanced Enzymatic Inhibition Effects and Potent in vitro and in vivo Antitumor Activities

Lei Zhang, Yingjie Zhang, C. James Chou et al. · ChemMedChem · 2013 · 23 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

Synthesis and biological characterization of ubenimex-fluorouracil conjugates for anti-cancer therapy

Yuqi Jiang, Xiaoyang Li, Jinning Hou et al. · European Journal of Medicinal Chemistry · 2017 · 23 citations · Full text

Medicine, Medicinal Chemistry, Oncology +15