Reduction of lactoferrin aggravates neuronal ferroptosis after intracerebral hemorrhagic stroke in hyperglycemic mice

Zhongnan Xiao, Danmin Shen, Ting Lan, +13

Redox Biology

Ferroptosis in oligodendrocyte progenitor cells mediates white matter injury after hemorrhagic stroke

Danmin Shen, Weihua Wu, Jing Liu, +14

Cell Death and Disease

Targeted macrophage phagocytosis by Irg1/itaconate axis improves the prognosis of intracerebral hemorrhagic stroke and peritonitis

Zhaoli Luo, Ziyang Sheng, Liye Hu, +20

EBioMedicine

IL-10 protects against OPC ferroptosis by regulating lipid reactive oxygen species levels post stroke

Weihua Wu, Zhaoli Luo, Danmin Shen, +12

Redox Biology

Itaconate protects ferroptotic neurons by alkylating GPx4 post stroke

Chao Wei, Zhongnan Xiao, Yanling Zhang, +20

Cell Death and Differentiation

Molecular NeuroscienceNeurophysiologyGpx4 Post StrokeNeuroprotectionNeuroscience +4

Virtual screening for Raf-1 kinase inhibitors based on pharmacophore model of substituted ureas

Huifang Li, Tao Lu, Tian Zhu, +5

European Journal of Medicinal Chemistry

Medicinal ChemistryVirtual ScreeningDrug TargetSubstituted UreasBiochemistry +9

IRG1/itaconate increases IL-10 release to alleviate mechanical and thermal hypersensitivity in mice after nerve injury

Qingyu Sun, Tingting Hu, Yurui Zhang, +20

Frontiers in Immunology

H3K9 trimethylation dictates neuronal ferroptosis through repressing <i>Tfr1</i>

Ting Lan, Liye Hu, Tingting Sun, +16

Journal of Cerebral Blood Flow & Metabolism

Inhibition of the LRRC8A channel promotes microglia/macrophage phagocytosis and improves outcomes after intracerebral hemorrhagic stroke

Jing Liu, Danmin Shen, Chao Wei, +19

iScience

The contribution of spinal dorsal horn astrocytes in neuropathic pain at the early stage of EAE

Yumeng Ding, Liye Hu, Xiaotong Wang, +14

Neurobiology of Disease

Pain MedicineImmunologyNeuropathic PainMolecular PainSpinal Disorder +18