PD-1 Blockade in Tumors with Mismatch-Repair Deficiency

Dung T. Le, Jennifer N. Uram, Hao Wang, +32

New England Journal of Medicine

Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade

Dung T. Le, Jennifer N. Durham, Kellie N. Smith, +43

Science

Solid TumorsPd-1 BlockadeImmunologyPathologyMismatch Repair Deficiency +14

Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies

Chetan Bettegowda, Mark Sausen, Rebecca Leary, +60

Science Translational Medicine

Dna AnalysisPathologyVarious Cancer TypesNucleic Acid BiomarkersTumor Biology +15

Genetic diversity of tumors with mismatch repair deficiency influences anti–PD-1 immunotherapy response

Rajarsi Mandal, Robert Samstein, Ken-Wing Lee, +21

Science

ImmunodeficienciesImmunologyPathologyMismatch Repair DeficiencyImmunotherapy +14

PD-1 blockade in tumors with mismatch repair deficiency.

Dung T. Le, Jennifer N. Uram, Hao Wang, +17

Journal of Clinical Oncology

Tumor BiologyTumoral PathologyMalignant DiseasePd-1 BlockadeMedicine +10

The Effect of Preservative and Temperature on the Analysis of Circulating Tumor DNA

Sonya Parpart-Li, Bjarne R. Bartlett, Maria Popoli, +12

Clinical Cancer Research

Noninvasive Detection of Microsatellite Instability and High Tumor Mutation Burden in Cancer Patients Treated with PD-1 Blockade

Andrew Georgiadis, Jennifer N. Durham, Laurel A. Keefer, +16

Clinical Cancer Research

Programmed death-1 blockade in mismatch repair deficient colorectal cancer.

Dung T. Le, Jennifer N. Uram, Hao Wang, +17

Journal of Clinical Oncology

Abstract 5606: Detection of circulating tumor DNA in early and late stage human malignancies

Chetan Bettegowda, Mark Sausen, Rebecca Leary, +9

Cancer Research

Cancer PathologyDna AnalysisPathologyAbstract 5606Nucleic Acid Biomarkers +16

Intratumoral Adaptive Immunosuppression and Type 17 Immunity in Mismatch Repair Proficient Colorectal Tumors

Nicolás J. Llosa, Brandon Luber, Ada Tam, +21

Clinical Cancer Research