Alexandre B. Hardy

Beta cell-specific Znt8 deletion in mice causes marked defects in insulin processing, crystallisation and secretion

Nadeeja Wijesekara, Feihan F. Dai, Alexandre B. Hardy et al. · Diabetologia · 2010 · 310 citations · Full text

Insulin Processing, Mice Causes, Molecular Physiology +8

The Furan Fatty Acid Metabolite CMPF Is Elevated in Diabetes and Induces β Cell Dysfunction

Kacey J. Prentice, Lemieux Luu, Emma M. Allister et al. · Cell Metabolism · 2014 · 154 citations · Full text

Metabolic Syndrome, Biochemistry, Physiology +7

The functional and molecular characterisation of human embryonic stem cell-derived insulin-positive cells compared with adult pancreatic beta cells

Christina Basford, Kacey J. Prentice, Alexandre B. Hardy et al. · Diabetologia · 2011 · 145 citations · Full text

Induced Pluripotent Stem Cell, Molecular Characterisation, Developmental Biology +7

Proinsulin Intermolecular Interactions during Secretory Trafficking in Pancreatic β Cells

Leena Haataja, Erik L. Snapp, J. J. Wright et al. · Journal of Biological Chemistry · 2012 · 87 citations · Full text

The loss of Sirt1 in mouse pancreatic beta cells impairs insulin secretion by disrupting glucose sensing

Lemieux Luu, Feihan F. Dai, Kacey J. Prentice et al. · Diabetologia · 2013 · 79 citations

Glucose Sensing, Signal Transduction, Diabetes +6