Estrogen Improves Insulin Sensitivity and Suppresses Gluconeogenesis via the Transcription Factor Foxo1

Hui Yan, Wangbao Yang, Fenghua Zhou, +14

Diabetes

Novel Mechanism of Foxo1 Phosphorylation in Glucagon Signaling in Control of Glucose Homeostasis

Yuxin Wu, Quan Pan, Hui Yan, +17

Diabetes

Hepatocyte FoxO1 Deficiency Protects From Liver Fibrosis via Reducing Inflammation and TGF-β1-mediated HSC Activation

Quan Pan, Mingming Gao, Da-Mi Kim, +9

Cellular and Molecular Gastroenterology and Hepatology

Cdk5 targets active Src for ubiquitin-dependent degradation by phosphorylating Src(S75)

Quan Pan, Fangfang Qiao, Chun Gao, +3

Cellular and Molecular Life Sciences

Protein FunctionSignal TransductionCell RegulationNatural SciencesReceptor Tyrosine Kinase +8

Administration of Danhong Injection to diabetic db/db mice inhibits the development of diabetic retinopathy and nephropathy

Mengyang Liu, Quan Pan, Yuanli Chen, +9

Scientific Reports

Epigallocatechin Gallate Inhibits Hepatic Glucose Production in Primary Hepatocytes via Downregulating PKA Signaling Pathways and Transcriptional Factor FoxO1

Xiaopeng Li, Yunmei Chen, Zheng Shen, +7

Journal of Agricultural and Food Chemistry

μM EgcgPathologyEgcg And/or GlucagonInsulin SignalingOxidative Stress +24

Phosphorylation of Forkhead Protein FoxO1 at S253 Regulates Glucose Homeostasis in Mice

Kebin Zhang, Xiaoqin Guo, Hui Yan, +17

Endocrinology

Glucagon regulates hepatic mitochondrial function and biogenesis through FOXO1

Wanbao Yang, Hui Yan, Quan Pan, +5

Journal of Endocrinology

Glucose HomeostasisMitochondrial BiologyRedox BiologyInsulin SignalingGlucagon Remains +16

Estrogen Protects Cardiac Function and Energy Metabolism in Dilated Cardiomyopathy Induced by Loss of Cardiac IRS1 and IRS2

Hui Yan, Wanbao Yang, Fenghua Zhou, +8

Circulation Heart Failure

Suppression of FOXO1 attenuates inflamm‐aging and improves liver function during aging

Wanbao Yang, Da Mi Kim, Wen G. Jiang, +7

Aging Cell