Gene F. Tutwiler

Identification of 2-tetradecylglycidyl coenzyme A as the active form of methyl 2-tetradecylglycidate (methyl palmoxirate) and its characterization as an irreversible, active site-directed inhibitor of carnitine palmitoyltransferase A in isolated rat liver mitochondria.

Timothy C. Kiorpes, David C. Hoerr, Winston Ho et al. · Journal of Biological Chemistry · 1984 · 152 citations · Full text

Action of the oral hypoglycemic agent 2-tetradecylglycidic acid on hepatic fatty acid oxidation and gluconeogenesis.

Gene F. Tutwiler, P. Dellevigne · Journal of Biological Chemistry · 1979 · 123 citations · Full text

Metabolic Syndrome, Lipid Metabolism, Biochemistry +10

Enhancement of the Hyperglycemic Activity of Human Growth Hormone by Enzymic Modification

U.J. Lewis, R. N. P. Singh, W. P. VANDERLAAN et al. · Endocrinology · 1977 · 77 citations

Human Growth, Glucose Tolerance Curves, Hyperglycemic Activity +18

Pharmacologic profile of methyl 2-tetradecylglycidate (McN-3716)—An orally effective hypoglycemic agent

Gene F. Tutwiler, Thomas J. Kirsch, Richard J. Mohrbacher et al. · Metabolism · 1978 · 76 citations

Diabetes Management, Medicine, Diabetes +5

Methyl 2-Tetradecylglycidate, An Orally Effective Hypoglycemic Agent that Inhibits Long Chain Fatty Acid Oxidation Selectively

Gene F. Tutwiler, Richard J. Mohrbacher, Winston Ho · Diabetes · 1979 · 71 citations

Metabolic Syndrome, Health Sciences, Biochemistry +14