The lysosomal cysteine protease cathepsin L regulates keratinocyte proliferation by control of growth factor recycling

Thomas Reinheckel, Sascha Hagemann, Susanne Dollwet-Mack, +6

Journal of Cell Science

Cell ProliferationDermatologyCell GrowthCtsl-knockout KeratinocytesCell Regulation +17

Cell Type-specific Functions of the Lysosomal Protease Cathepsin L in the Heart

Daniel Spira, Jörg Stypmann, Desmond J. Tobin, +8

Journal of Biological Chemistry

Cardiac MuscleImmunologyProteasomeCardiovascular FunctionCellular Physiology +20

Induction of M2-macrophages by tumour cells and tumour growth promotion by M2-macrophages: A quid pro quo in pancreatic cancer

Lars-Ivo Partecke, C Günther, Sascha Hagemann, +10

Pancreatology

Pancreatic CancerMedicineQuid Pro QuoImmunologyAutophagy +9

The human cysteine protease cathepsin V can compensate for murine cathepsin L in mouse epidermis and hair follicles

Sascha Hagemann, Thomas Günther, Julia Dennemärker, +5

European Journal of Cell Biology

InflammationMouse EpidermisMedicineImmunologyMurine Cathepsin L +4

Macrophages promote tumour growth and liver metastasis in an orthotopic syngeneic mouse model of colon cancer

Judith Kruse, Wolfram von Bernstorff, Katja Evert, +7

International Journal of Colorectal Disease

Tumor BiologyTumour GrowthMedicineLiver PhysiologyImmunology +11

Eukaryotic elongation factor 2 is a prognostic marker and its kinase a potential therapeutic target in HCC

Leona L. Pott, Sascha Hagemann, Henning Reis, +9

Oncotarget

Expression of human cathepsin L or human cathepsin V in mouse thymus mediates positive selection of T helper cells in cathepsin L knock-out mice

Lisa Sevenich, Sascha Hagemann, Christina Stoeckle, +3

Biochimie

InflammationT Helper CellsAutoimmune DiseaseLymphocyte DevelopmentImmune Regulation +9

A structured proteomic approach identifies 14-3-3Sigma as a novel and reliable protein biomarker in panel based differential diagnostics of liver tumors

Henning Reis, Carolin Pütter, Dominik A. Megger, +12

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Loss of Survivin influences liver regeneration and is associated with impaired Aurora B function

Sascha Hagemann, Jeremias Wohlschlaeger, Simon Bertram, +8

Cell Death and Differentiation

HepatologyLiver PhysiologySurvivin InfluencesPathologyLiver Disease +4

Proteome Analysis of a Hepatocyte-Specific BIRC5 (Survivin)-Knockout Mouse Model during Liver Regeneration

Thilo Bracht, Sascha Hagemann, Marius Loscha, +7

Journal of Proteome Research

ApoptosisImmunologyCell DeathCholangiopathiesBirc5-knockout Mice +16