Changge Guan

Pooled CRISPR interference screening enables genome-scale functional genomics study in bacteria with superior performance

Tianmin Wang, Changge Guan, Jiahui Guo et al. · Nature Communications · 2018 · 262 citations · Full text

Improved sgRNA design in bacteria via genome-wide activity profiling

Jiahui Guo, Tianmin Wang, Changge Guan et al. · Nucleic Acids Research · 2018 · 96 citations · Full text

Engineering, Microbial Pathogens, Molecular Biology +21

Biosensor-assisted transcriptional regulator engineering for Methylobacterium extorquens AM1 to improve mevalonate synthesis by increasing the acetyl-CoA supply

Wei‐Fan Liang, Lanyu Cui, Jinyu Cui et al. · Metabolic Engineering · 2016 · 72 citations

Biosynthesis, Engineering, Molecular Biotechnology +10

Breeding of Methanol-Tolerant <i>Methylobacterium extorquens</i> AM1 by Atmospheric and Room Temperature Plasma Mutagenesis Combined With Adaptive Laboratory Evolution

Lanyu Cui, Shanshan Wang, Changge Guan et al. · Biotechnology Journal · 2018 · 32 citations

Engineering, Molecular Biology, Biosynthesis +17

Computational exploration of global venoms for antimicrobial discovery with Venomics artificial intelligence

Changge Guan, Marcelo D. T. Torres, Sufen Li et al. · Nature Communications · 2025 · 15 citations · Full text