Nathan A. Siegfried

RNA motif discovery by SHAPE and mutational profiling (SHAPE-MaP)

Nathan A. Siegfried, Steven Busan, Greggory M. Rice et al. · Nature Methods · 2014 · 712 citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +14

Selective 2′-hydroxyl acylation analyzed by primer extension and mutational profiling (SHAPE-MaP) for direct, versatile and accurate RNA structure analysis

Matthew J. Smola, Greggory M. Rice, Steven Busan et al. · Nature Protocols · 2015 · 435 citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +14

Folding Cooperativity in RNA and DNA Is Dependent on Position in the Helix

Nathan A. Siegfried, Shana Metzger, Philip C. Bevilacqua · Biochemistry · 2007 · 48 citations

Life Sciences, Biochemistry, Molecular Biology +14

Mechanistic Characterization of the HDV Genomic Ribozyme: Solvent Isotope Effects and Proton Inventories in the Absence of Divalent Metal Ions Support C75 as the General Acid

Andrea L. Cerrone-Szakal, Nathan A. Siegfried, Philip C. Bevilacqua · Journal of the American Chemical Society · 2008 · 45 citations

Life Sciences, Biochemistry, Molecular Biology +13

Role of Unsatisfied Hydrogen Bond Acceptors in RNA Energetics and Specificity

Nathan A. Siegfried, Ryszard Kierzek, Philip C. Bevilacqua · Journal of the American Chemical Society · 2010 · 37 citations

Life Sciences, Chemistry, Molecular Biology +17