Zichong Li

The BET bromodomain inhibitor JQ1 activates HIV latency through antagonizing Brd4 inhibition of Tat-transactivation

Zichong Li, Jia Guo, Yuntao Wu et al. · Nucleic Acids Research · 2012 · 297 citations · Full text

AFF1 is a ubiquitous P-TEFb partner to enable Tat extraction of P-TEFb from 7SK snRNP and formation of SECs for HIV transactivation

Huasong Lu, Zichong Li, Yuhua Xue et al. · Proceedings of the National Academy of Sciences · 2013 · 77 citations · Full text

Complete Sec, Immunology, Molecular Biology +19

Gene target specificity of the Super Elongation Complex (SEC) family: how HIV-1 Tat employs selected SEC members to activate viral transcription

Huasong Lu, Zichong Li, Wei Zhang et al. · Nucleic Acids Research · 2015 · 68 citations · Full text

Viral Replication, Genetics, Aff4 Act +20

The Ubiquitin Ligase Siah1 Controls ELL2 Stability and Formation of Super Elongation Complexes to Modulate Gene Transcription

Min Liu, Joanne Hsu, Caleb K. Chan et al. · Molecular Cell · 2012 · 63 citations · Full text

Transcriptional Regulation, Super Elongation Complexes, Molecular Regulation +9

The KAT5-Acetyl-Histone4-Brd4 axis silences HIV-1 transcription and promotes viral latency

Zichong Li, Uri Mbonye, Zeming Feng et al. · PLoS Pathogens · 2018 · 53 citations · Full text

Viral Replication, Immunology, Molecular Biology +17