Sandra Piras

Discovery of potent pteridine reductase inhibitors to guide antiparasite drug development

Antonio Cavazzuti, Giuseppe Paglietti, William N. Hunter et al. · Proceedings of the National Academy of Sciences · 2008 · 157 citations · Full text

Crystal Structure, Bioorganic Chemistry, Antiparasitic Agent +17

Quinoxaline chemistry. Part 7. 2-[aminobenzoates]- and 2-[aminobenzoylglutamate]-quinoxalines as classical antifolate agents. Synthesis and evaluation of in vitro anticancer, anti-HIV and antifungal activity.

Mario Loriga, Sandra Piras, Paolo Sanna et al. · PubMed · 1997 · 101 citations

Quinoline tricyclic derivatives. Design, synthesis and evaluation of the antiviral activity of three new classes of RNA-dependent RNA polymerase inhibitors

Antonio Carta, Irene Briguglio, Sandra Piras et al. · Bioorganic & Medicinal Chemistry · 2011 · 75 citations

Antiviral Activity, Medicine, Antiviral Drug Development +9

Quinoxaline chemistry. Part XVII. Methyl [4-(substituted 2-quinoxalinyloxy) phenyl] acetates and ethyl N-{[4-(substituted 2-quinoxalinyloxy) phenyl] acetyl} glutamates analogs of methotrexate: synthesis and evaluation of in vitro anticancer activity

Sandra Piras, Mario Loriga, Giuseppe Paglietti · Il Farmaco · 2004 · 54 citations

Quinoxaline Chemistry, Molecular Pharmacology, Medicinal Chemistry +13

Novel 3‐benzoyl‐2‐piperazinylquinoxaline derivatives as potential antitumor agents

Sandra Piras, Mario Loriga, Antonio Carta et al. · Journal of Heterocyclic Chemistry · 2006 · 54 citations · Full text

Pharmacotherapy, New Benzoylquinoxaline Derivatives, Pharmaceutical Chemistry +16