Discovery of potent pteridine reductase inhibitors to guide antiparasite drug development

Antonio Cavazzuti, Giuseppe Paglietti, William N. Hunter, +10

Proceedings of the National Academy of Sciences

Crystal StructureBioorganic ChemistryAntiparasitic AgentPharmacotherapyChemical Biology +15

Quinoxaline chemistry. Part 7. 2-[aminobenzoates]- and 2-[aminobenzoylglutamate]-quinoxalines as classical antifolate agents. Synthesis and evaluation of in vitro anticancer, anti-HIV and antifungal activity.

Mario Loriga, Sandra Piras, Paolo Sanna, +1

PubMed

Quinoline tricyclic derivatives. Design, synthesis and evaluation of the antiviral activity of three new classes of RNA-dependent RNA polymerase inhibitors

Antonio Carta, Irene Briguglio, Sandra Piras, +11

Bioorganic & Medicinal Chemistry

Antiviral ActivityMedicineAntiviral Drug DevelopmentAntiviral TherapyMolecular Biology +7

Quinoxaline chemistry. Part XVII. Methyl [4-(substituted 2-quinoxalinyloxy) phenyl] acetates and ethyl N-{[4-(substituted 2-quinoxalinyloxy) phenyl] acetyl} glutamates analogs of methotrexate: synthesis and evaluation of in vitro anticancer activity

Sandra Piras, Mario Loriga, Giuseppe Paglietti

Il Farmaco

Quinoxaline ChemistryMolecular PharmacologyMedicinal ChemistryPart XviiPharmaceutical Science +11

Novel 3‐benzoyl‐2‐piperazinylquinoxaline derivatives as potential antitumor agents

Sandra Piras, Mario Loriga, Antonio Carta, +3

Journal of Heterocyclic Chemistry

PharmacotherapyNew Benzoylquinoxaline DerivativesPharmaceutical ChemistryPre-clinical PharmacologyMolecular Pharmacology +14

Synthesis and Biological Evaluation of Novel Indole-Derived Thioureas

Giuseppina Sanna, Silvia Madeddu, Gabriele Giliberti, +10

Molecules

Phytochemical Compositions and Biological Activities of Essential Oils from the Leaves, Rhizomes and Whole Plant of Hornstedtia bella Škorničk

Matthew Gavino Donadu, Nhan Trong Le, Đức Việt Hồ, +15

Antibiotics

Synthesis and In Vitro Evaluation of the Anti-Viral Activity of N-[4-(1H(2H)-benzotriazol-1(2)-yl)phenyl]alkylcarboxamides

Antonio Carta, Giovanni Loriga, Sandra Piras, +8

Medicinal Chemistry

Crystal StructureMedicinal ChemistryTitle CompoundsPolio VirusMedicine +13

Synthesis of Variously Substituted 3-Phenoxymethyl Quinoxalin-2-Ones and Quinoxalines Capable to Potentiate In Vitro the Antiproliferative Activity of Anticancer Drugs in Multi-Drug Resistant Cell Lines

Roberta Loddo, Paolo La Colla, Bernardetta Busonera, +5

Medicinal Chemistry

Enhancement of antimicrobial activity of pump inhibitors associating drugs

Donatella Usai, Matthew Gavino Donadu, Alessandra Bua, +6

The Journal of Infection in Developing Countries