QRS widening and QT prolongation under bupropion: a unique cardiac electrophysiological profile

Bertrand Caillier, Sylvie Pilote, Annie Castonguay, +9

Fundamental and Clinical Pharmacology

Estradiol regulates human QT-interval: acceleration of cardiac repolarization by enhanced KCNH2 membrane trafficking

Lars Anneken, Stefan Baumann, Patrick Vigneault, +15

European Heart Journal

Tizanidine (Zanaflex)

Nisrin Kaddar, Patrick Vigneault, Sylvie Pilote, +3

Journal of Cardiovascular Pharmacology and Therapeutics

Potassium HomeostasisMolecular PharmacologyCardiac MuscleCardiovascular DiseaseGuinea Pigs +11

Induced KCNQ1 autoimmunity accelerates cardiac repolarization in rabbits: Potential significance in arrhythmogenesis and antiarrhythmic therapy

Jin Li, Ange Maguy, James Elber Duverger, +6

Heart Rhythm

InflammationPotential SignificanceCardiomyopathyHeart FailureMolecular Physiology +12

Prolongation of Cardiac Ventricular Repolarization Under Paliperidone: How and How Much?

Patrick Vigneault, Nisrin Kaddar, Sarah Bourgault, +5

Journal of Cardiovascular Pharmacology

Titin-truncating variants in hiPSC cardiomyocytes induce pathogenic proteinopathy and sarcomere defects with preserved core contractile machinery

Guanyi Huang, Anjali Bisaria, Devin L. Wakefield, +14

Stem Cell Reports

Calcium‐dependent potassium channels control proliferation of cardiac progenitor cells and bone marrow‐derived mesenchymal stem cells

Patrick Vigneault, Patrice Naud, Xiaoyan Qi, +4

The Journal of Physiology

Rosuvastatin Blocks hERG Current and Prolongs Cardiac Repolarization

Isabelle Plante, Patrick Vigneault, Benoît Drolet, +1

Journal of Pharmaceutical Sciences

Heart FailureProlongs Cardiac RepolarizationCardiovascular DiseaseMedicinePhysiology +5

Iloperidone (Fanapt®), a novel atypical antipsychotic, is a potent HERG blocker and delays cardiac ventricular repolarization at clinically relevant concentration

Patrick Vigneault, Sylvie Pilote, Dany Patoine, +2

Pharmacological Research

Psychotropic MedicationPharmacologyNovel Atypical AntipsychoticPotent Herg BlockerNeuropharmacology +3

Galantamine (Reminyl®) delays cardiac ventricular repolarization and prolongs the QT interval by blocking the HERG current

Patrick Vigneault, Sarah Bourgault, Nisrin Kaddar, +5

European Journal of Pharmacology

Cardiac MuscleHeart FailureCardiac Ventricular RepolarizationMedicinePhysiology +7