John‐Demian Sauer

The<i>N</i>-Ethyl-<i>N</i>-Nitrosourea-Induced<i>Goldenticket</i>Mouse Mutant Reveals an Essential Function of<i>Sting</i>in the<i>In Vivo</i>Interferon Response to<i>Listeria monocytogenes</i>and Cyclic Dinucleotides

John‐Demian Sauer, Katia Troha, Jakob von Moltke et al. · Infection and Immunity · 2010 · 553 citations · Full text

Microbial Pathogens, Gt Mice, Innate Immune System +20

Listeria monocytogenes Triggers AIM2-Mediated Pyroptosis upon Infrequent Bacteriolysis in the Macrophage Cytosol

John‐Demian Sauer, Chelsea E. Witte, Jason Zemansky et al. · Cell Host & Microbe · 2010 · 311 citations

Triggers Aim2-mediated Pyroptosis, Virulence Factor, Pathogenesis +8

The Cyclic Dinucleotide c-di-AMP Is an Allosteric Regulator of Metabolic Enzyme Function

Kamakshi Sureka, Philip H. Choi, Mimi R. Precit et al. · Cell · 2014 · 219 citations · Full text

Metabolic Enzyme Function, Aldo-keto Reductase, Cellular Enzymology +7

Cyclic di-AMP Is Critical for Listeria monocytogenes Growth, Cell Wall Homeostasis, and Establishment of Infection

Chelsea E. Witte, Aaron T. Whiteley, Thomas Burke et al. · mBio · 2013 · 200 citations · Full text

Microbial Pathogens, Bacteriology, Innate Immunity +22

An HD-domain phosphodiesterase mediates cooperative hydrolysis of c-di-AMP to affect bacterial growth and virulence

TuAnh N. Huynh, Shukun Luo, Daniel A. Pensinger et al. · Proceedings of the National Academy of Sciences · 2015 · 198 citations · Full text