Ying‐Yi Chen

Identification of a cellularly active SIRT6 allosteric activator

Zhimin Huang, Junxing Zhao, Wei Deng et al. · Nature Chemical Biology · 2018 · 268 citations

Life Sciences, Biochemistry, Molecular Biology +9

A novel SIRT6 activator ameliorates neuroinflammation and ischemic brain injury via EZH2/FOXC1 axis

Tailin He, Jialin Shang, Chenglong Gao et al. · Acta Pharmaceutica Sinica B · 2020 · 134 citations · Full text

Life Sciences, Immunology, Neuroscience +17

Crystal Structures of PI3Kα Complexed with PI103 and Its Derivatives: New Directions for Inhibitors Design

Yanlong Zhao, Xi Zhang, Ying‐Yi Chen et al. · ACS Medicinal Chemistry Letters · 2013 · 101 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Analysis of peptides and proteins affinity-bound to iron oxide nanoparticles by MALDI MS

Sarah Y. Chang, Nan-yan Zheng, Chee‐Shan Chen et al. · Journal of the American Society for Mass Spectrometry · 2007 · 68 citations

Natural Sciences, Biochemistry, Analytical Chemistry +16

MDL-800, an allosteric activator of SIRT6, suppresses proliferation and enhances EGFR-TKIs therapy in non-small cell lung cancer

Jialin Shang, Shaobo Ning, Ying‐Yi Chen et al. · Acta Pharmacologica Sinica · 2020 · 66 citations · Full text

Medicine, Oncology, Pharmacology +16