Christopher M. Hosfield

Crystal structure of calpain reveals the structural basis for Ca2+-dependent protease activity and a novel mode of enzyme activation

Christopher M. Hosfield · The EMBO Journal · 1999 · 356 citations · Full text

Crystal Structure, Protein Function, Biochemistry +8

A Ca2+ Switch Aligns the Active Site of Calpain

Tudor Moldoveanu, Christopher M. Hosfield, Daniel Lim et al. · Cell · 2002 · 326 citations · Full text

Ca2+ Switch Aligns, Signal Transduction, Molecular Physiology +8

Dysregulation of renal vitamin D metabolism in the uremic rat

Christian Helvig, Dominic Cuerrier, Christopher M. Hosfield et al. · Kidney International · 2010 · 110 citations · Full text

Urology, Renal Function, Kidney Research +9

Calpain silencing by a reversible intrinsic mechanism

Tudor Moldoveanu, Christopher M. Hosfield, Daniel Lim et al. · Nature Structural & Molecular Biology · 2003 · 70 citations

Biophysical Modeling, Biophysical Aspect, Mechanism Of Action +6

A Multidimensional Analytical Comparison of Remicade and the Biosimilar Remsima

Karthik Pisupati, Yuwei Tian, Solomon Z. Okbazghi et al. · Analytical Chemistry · 2017 · 69 citations · Full text

Engineering, Immunology, Peptide Science +27