Jaakko Pohjoismäki

Alterations to the expression level of mitochondrial transcription factor A, TFAM, modify the mode of mitochondrial DNA replication in cultured human cells

Jaakko Pohjoismäki, Sjoerd Wanrooij, Anne K. Hyvärinen et al. · Nucleic Acids Research · 2006 · 165 citations · Full text

Genetics, Molecular Biology, Mitochondrial Biogenesis +16

Ciprofloxacin impairs mitochondrial DNA replication initiation through inhibition of Topoisomerase 2

Anu Hangas, Koit Aasumets, Nina J Kekäläinen et al. · Nucleic Acids Research · 2018 · 146 citations · Full text

Mitochondrial Function, Biochemistry, Mitochondrial Dna +14

Expression of catalytic mutants of the mtDNA helicase Twinkle and polymerase POLG causes distinct replication stalling phenotypes

Sjoerd Wanrooij, Steffi Goffart, Jaakko Pohjoismäki et al. · Nucleic Acids Research · 2007 · 145 citations · Full text

Intense Debate, Genetics, Molecular Biology +16

The mitochondrial transcription termination factor mTERF modulates replication pausing in human mitochondrial DNA

Anne K. Hyvärinen, Jaakko Pohjoismäki, Aurelio Reyes et al. · Nucleic Acids Research · 2007 · 133 citations · Full text

Mammalian Mitochondrial DNA Replication Intermediates Are Essentially Duplex but Contain Extensive Tracts of RNA/DNA Hybrid

Jaakko Pohjoismäki, J. Bradley Holmes, Stuart Wood et al. · Journal of Molecular Biology · 2010 · 126 citations

Dna, Rna/dna Hybrid, Mitochondrial Function +8