William Geiss

Design, Synthesis, and Structure−Activity Relationships of Novel 2-Substituted Pyrazinoylguanidine Epithelial Sodium Channel Blockers:  Drugs for Cystic Fibrosis and Chronic Bronchitis

Andrew J. Hirsh, Bruce F. Molino, Jianzhong Zhang et al. · Journal of Medicinal Chemistry · 2006 · 76 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Synthesis and Pharmacological Evaluation of Novel γ-Aminobutyric Acid Type B (GABA_B) Receptor Agonists as Gastroesophageal Reflux Inhibitors

Christer Alstermark, Kosrat Amin, Sean R. Dinn et al. · Journal of Medicinal Chemistry · 2008 · 48 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +16

A Stereospecific Synthesis of 24(<i>S</i>)-Hydroxyvitamin D₂, a Prodrug for 1α,24(<i>S</i>)-Dihydroxyvitamin D₂

Lisa D. Coutts, William Geiss, Brian T. Gregg et al. · Organic Process Research & Development · 2002 · 20 citations

Pharmacy, Biochemistry, Medicinal Chemistry +15

Synthesis and SAR development of novel P2X7 receptor antagonists for the treatment of pain: Part 2

Stephanie Brumfield, Julius J. Matasi, Deen Tulshian et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 17 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Effects of (2<i>R</i>)‐(3‐amino‐2‐fluoropropyl)sulphinic acid (AFPSiA) on transient lower oesophageal sphincter relaxation in dogs and mechanism of hypothermic effects in mice

Anders Lehmann, Ann Aurell Holmberg, Ulhas Bhatt et al. · British Journal of Pharmacology · 2005 · 11 citations · Full text

Medicine, Pharmacology, Clinical Pharmacology +10