Yasunobu Yamashita

Selective degradation of histone deacetylase 8 mediated by a proteolysis targeting chimera (PROTAC)

Jiranan Chotitumnavee, Yasunobu Yamashita, Yukari Takahashi et al. · Chemical Communications · 2022 · 51 citations

Life Sciences, Biochemistry, Molecular Biology +16

Identification of Potent and Selective Inhibitors of Fat Mass Obesity-Associated Protein Using a Fragment-Merging Approach

Muthuraj Prakash, Yukihiro Itoh, Yoshie Fujiwara et al. · Journal of Medicinal Chemistry · 2021 · 40 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Mepenzolate bromide displays beneficial effects in a mouse model of chronic obstructive pulmonary disease

Ken‐ichiro Tanaka, Tomoaki Ishihara, Toshifumi Sugizaki et al. · Nature Communications · 2013 · 34 citations · Full text

Pharmacy, Pharmacology, Pharmacotherapy +7

Prediction of Protein−compound Binding Energies from Known Activity Data: Docking‐score‐based Method and its Applications

Yoshifumi Fukunishi, Yasunobu Yamashita, Tadaaki Mashimo et al. · Molecular Informatics · 2018 · 26 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Design, Synthesis, and Biological Evaluation of Lysine Demethylase 5 C Degraders

Tetsuya Iida, Yukihiro Itoh, Yukari Takahashi et al. · ChemMedChem · 2021 · 25 citations

Pharmacy, Medicinal Chemistry, Oncology +13