Vinzenz Särchen

CRISPR/Cas9 editing of NKG2A improves the efficacy of primary CD33-directed chimeric antigen receptor natural killer cells

Tobias Bexte, Nawid Albinger, Ahmad Al Ajami et al. · Nature Communications · 2024 · 54 citations · Full text

Genome Surgery, Crispr/cas9 Editing, Immunology +7

Palmitoylation is required for TNF-R1 signaling

Philipp Zingler, Vinzenz Särchen, Timo Glatter et al. · Cell Communication and Signaling · 2019 · 50 citations · Full text

TNF induced cleavage of HSP90 by cathepsin D potentiates apoptotic cell death

Jürgen Fritsch, Ricarda Fickers, Jan Klawitter et al. · Oncotarget · 2016 · 34 citations · Full text

Role of ubiquitination and proteolysis in the regulation of pro- and anti-apoptotic TNF-R1 signaling

Jürgen Fritsch, Philipp Zingler, Vinzenz Särchen et al. · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · 2017 · 24 citations

Reductive Stress, Signal Transduction, Signaling Pathway +10

Pediatric multicellular tumor spheroid models illustrate a therapeutic potential by combining BH3 mimetics with Natural Killer (NK) cell-based immunotherapy

Vinzenz Särchen, Senthan Shanmugalingam, Sarah Kehr et al. · Cell Death Discovery · 2022 · 21 citations · Full text